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一家职业病医院330例患者的欧洲标准斑贴试验结果比较

Comparison of European Standard Patch Test Results of 330 Patients from an Occupational Diseases Hospital.

作者信息

Gündüz Özge, Aytekin Aslı, Tutkun Engin, Yılmaz Hınç

机构信息

Ufuk University Faculty of Medicine, Department of Dermatology, Ankara, Turkey.

Department of Dermatology, Ankara Occupational Diseases Hospital, Ankara, Turkey.

出版信息

Dermatol Res Pract. 2016;2016:9421878. doi: 10.1155/2016/9421878. Epub 2016 Oct 11.

Abstract

Contact dermatitis (CD) is the most prevalent occupational skin disease with a significant impact on quality of life. Patch testing is used for the identification of responsible allergens which may improve protective and preventive measures in the workplace. Herein, we aim to identify the demographic characteristics and occupation of patients with early diagnosis of occupational CD and compare patch test results. The study included 330 patients referred to our clinic between April 2009 and April 2011 and who were patch-tested with 28-allergen European Standard Test. 126 (38%) patients were female and 204 (62%) were male with a mean age of 36.12 (±13.13) years. Positive allergic reactions were observed in 182 (55%) patients. Nickel sulphate (41/126) and potassium dichromate (39/204) were significantly the most common allergens in women and men, respectively ( < 0.005). Additionally, the most common occupation in women was household activities (83/126) and in men was manufacturing (80/204). The allergens to which people become sensitized differ according to their working environment and occupation. Classification of occupations is important for identification of sensitization risks and monitoring of changes in allergen distribution of different occupations.

摘要

接触性皮炎(CD)是最常见的职业性皮肤病,对生活质量有重大影响。斑贴试验用于识别可能改善工作场所防护和预防措施的相关过敏原。在此,我们旨在确定早期诊断为职业性接触性皮炎患者的人口统计学特征和职业,并比较斑贴试验结果。该研究纳入了2009年4月至2011年4月间转诊至我们诊所并接受28种过敏原欧洲标准试验斑贴试验的330例患者。126例(38%)患者为女性,204例(62%)为男性,平均年龄为36.12(±13.13)岁。182例(55%)患者观察到阳性过敏反应。硫酸镍(41/126)和重铬酸钾(39/204)分别是女性和男性中最常见的过敏原(<0.005)。此外,女性中最常见的职业是家务活动(83/126),男性中最常见的职业是制造业(80/204)。人们致敏的过敏原因工作环境和职业而异。职业分类对于识别致敏风险和监测不同职业过敏原分布的变化很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdeb/5078646/b2403016e4ea/DRP2016-9421878.001.jpg

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