Sharma Priyanka, Verma Yogesh, Sahu Khageswar, Kumar Sudhir, Varma Amit V, Kumawat Jyoti, Gupta Pradeep Kumar
Laser Biomedical Applications Section, Raja Ramanna Centre for Advanced Technology, Indore, 452013, India.
Homi Bhabha National Institute, Mumbai, 400094, India.
Lasers Med Sci. 2017 Jan;32(1):143-150. doi: 10.1007/s10103-016-2096-3. Epub 2016 Nov 2.
We report the use of spectral domain polarization sensitive optical coherence tomography for ex-vivo imaging of human oral mandibular tissue samples. Our results show that compared to the changes observed in the epithelium thickness and the decay constant of A-scan intensity profile, a much larger degree of change was observed in the phase retardation for tissue sites progressing from normal to the malignant state. These results suggest that monitoring of tissue retardance can help in better differentiation of normal and cancerous oral tissue sites.
我们报告了使用光谱域偏振敏感光学相干断层扫描技术对人体口腔下颌组织样本进行离体成像的情况。我们的结果表明，与上皮厚度和A扫描强度轮廓衰减常数的变化相比，从正常状态发展到恶性状态的组织部位的相位延迟变化程度要大得多。这些结果表明，监测组织延迟有助于更好地区分正常和癌性口腔组织部位。
