TU Dresden, Faculty of Medicine Carl Gustav Carus, Anesthesiology and Intensive Care Medicine, Clini, Germany.
TU Dresden, Faculty of Medicine Carl Gustav Carus, Department of Medical Physics and Biomedical Engi, Germany.
J Biomed Opt. 2017 Dec;22(12):1-17. doi: 10.1117/1.JBO.22.12.121717.
Since optical coherence tomography (OCT) provides three-dimensional high-resolution images of biological tissue, the benefit of polarization contrast in the field of dentistry is highlighted in this study. Polarization-sensitive OCT (PS OCT) with phase-sensitive recording is used for imaging dental and mucosal tissues in the human oral cavity in vivo. An enhanced polarization contrast of oral structures is reached by analyzing the signals of the co- and crosspolarized channels of the swept source PS OCT system quantitatively with respect to reflectivity, retardation, optic axis orientation, and depolarization. The calculation of these polarization parameters enables a high tissue-specific contrast imaging for the detailed physical interpretation of human oral hard and soft tissues. For the proof-of-principle, imaging of composite restorations and mineralization defects at premolars as well as gingival, lingual, and labial oral mucosa was performed in vivo within the anterior oral cavity. The achieved contrast-enhanced results of the investigated human oral tissues by means of polarization-sensitive imaging are evaluated by the comparison with conventional intensity-based OCT.
由于光学相干断层扫描（OCT）可提供生物组织的三维高分辨率图像，因此本研究突出了偏振对比在牙科领域的优势。偏振敏感 OCT（PS OCT）采用具有相位敏感记录的方法对人体口腔中的牙齿和黏膜组织进行了体内成像。通过对扫频源 PS OCT 系统的共极化和交叉极化通道信号进行定量分析，根据反射率、延迟、光轴方向和去偏振度来获得口腔结构的增强偏振对比度。这些偏振参数的计算可实现高组织特异性对比成像，从而对人体口腔硬组织和软组织进行详细的物理解释。为了验证原理，对前口腔内的磨牙复合修复体和矿化缺陷以及牙龈、舌侧和唇侧口腔黏膜进行了体内成像。通过与传统基于强度的 OCT 进行比较，评估了偏振敏感成像对所研究的人体口腔组织的增强对比度效果。
