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美国成年人中潜伏性弓形虫病与多种身体指标之间无关联。

No association between latent toxoplasmosis and multiple body measures in U.S. adults.

作者信息

Berrett Andrew N, Gale Shawn D, Erickson Lance D, Brown Bruce L, Hedges Dawson W

机构信息

Department of Psychology, Brigham Young University, Provo, Utah, USA.

The Neuroscience Center, Brigham Young University, Provo, Utah, USA.

出版信息

Folia Parasitol (Praha). 2016 Oct 14;63:2016.034. doi: 10.14411/fp.2016.034.

DOI:10.14411/fp.2016.034
PMID:27827337
Abstract

Toxoplasma gondii (Nicolle et Manceaux, 1908) is an intracellular parasite that can cause ongoing latent infection persisting for the duration of a non-definitive host's life. Affecting approximately one-third of the world's population, latent toxoplasmosis has been associated with neuropsychological outcomes and a previous report suggested an association between latent toxoplasmosis and adult height. Given the large number of people with latent toxoplasmosis and its potential associations with human height, we sought to better understand the association between latent toxoplasmosis and human morphology by evaluating seropositivity for T. gondii and multiple body measures reported in the National Health and Nutrition Examination Survey III (NHANES III) and in the more recent continuous NHANES data sets from the United States Centers for Disease Control and Prevention for which data on T. gondii are available. In these analyses, latent toxoplasmosis was not associated with any of the body measures assessed in the NHANES datasets even after taking into account interactions between latent toxoplasmosis and testosterone suggesting that in these samples, latent toxoplasmosis is not associated with adult morphology including height.

摘要

刚地弓形虫(Nicolle和Manceaux,1908年)是一种细胞内寄生虫,可导致在非终末宿主的生命周期内持续存在的潜伏感染。潜伏性弓形虫病影响着全球约三分之一的人口,它与神经心理学结果有关,并且先前有报告表明潜伏性弓形虫病与成年人身高之间存在关联。鉴于潜伏性弓形虫病患者数量众多及其与人类身高的潜在关联,我们试图通过评估美国疾病控制与预防中心国家健康与营养检查调查III(NHANES III)以及最近可获取弓形虫数据的连续NHANES数据集中报告的弓形虫血清阳性率和多项身体测量指标,来更好地了解潜伏性弓形虫病与人类形态之间的关联。在这些分析中,即使在考虑了潜伏性弓形虫病与睾酮之间的相互作用后,潜伏性弓形虫病与NHANES数据集中评估的任何身体测量指标均无关联,这表明在这些样本中潜伏性弓形虫病与包括身高在内的成人形态无关。

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