Larsson B, Seidell J, Svärdsudd K, Welin L, Tibblin G, Wilhelmsen L, Björntorp P
Department of Medicine I, Sahlgren's Hospital, Goteberg, Sweden.
Appetite. 1989 Aug;13(1):37-44. doi: 10.1016/0195-6663(89)90025-1.
Recent studies suggest that cardiovascular disease is associated with abdominal distribution of adipose tissue rather than obesity in terms of total body fat. A number of other variables, known to be associated with obesity, were therefore examined in a cohort of randomly selected middle-aged men in relation to abdominal distribution of adipose tissue, measured as the ratio of the circumferences of the waist and hips (WHR), as well as to degree of obesity, measured as body mass index (BMI). These variables included anthropometric variables, cardiovascular risk factors as well as socioeconomic factors and physical health. Increased WHR, independent of BMI, was negatively associated with height, and hip circumference. Positive associations were found with blood pressure, cholesterol, triglycerides, fibrinogen and smoking. In addition positive associations were found with low social class and social group, illness in terms of sick leave, frequent use of health facilities such as X-rays, as well as diseases such as peptic ulcer. In sharp contrast to this, BMI, independent of WHR, was not associated with physical health variables or social class. Generalized obesity seemed to be associated with good health in the variables measured. There were positive associations to various anthropometric variables, including lean body mass. High BMI was also associated with elevated blood pressure and triglycerides. Several of the indicators of poor health traditionally associated with obesity thus do not seem to be characteristic for obesity in middle-aged men selected at random from the population but rather for an abdominal fat distribution, independent of obesity.
近期研究表明，就总体脂肪而言，心血管疾病与腹部脂肪分布有关，而非与肥胖有关。因此，在一组随机挑选的中年男性队列中，研究了许多其他已知与肥胖相关的变量，这些变量与腹部脂肪分布（以腰围与臀围之比（腰臀比）衡量）以及肥胖程度（以体重指数（BMI）衡量）的关系。这些变量包括人体测量学变量、心血管危险因素以及社会经济因素和身体健康状况。独立于BMI的腰臀比增加与身高和臀围呈负相关。与血压、胆固醇、甘油三酯、纤维蛋白原和吸烟呈正相关。此外，与低社会阶层和社会群体、病假方面的疾病、频繁使用X射线等医疗设施以及消化性溃疡等疾病呈正相关。与此形成鲜明对比的是，独立于腰臀比的BMI与身体健康变量或社会阶层无关。在测量的变量中，全身性肥胖似乎与健康状况良好有关。与各种人体测量学变量呈正相关，包括瘦体重。高BMI也与血压升高和甘油三酯升高有关。因此，传统上与肥胖相关的一些健康不佳指标似乎并非随机从人群中挑选的中年男性肥胖的特征，而是腹部脂肪分布的特征，与肥胖无关。
