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放射性外阴硬化性苔藓:医学文献中的首例报告。

Radiation-induced lichen sclerosus of the vulva : First report in the medical literature.

作者信息

Edwards Lisa R, Privette Emily D, Patterson James W, Tchernev Georgi, Chokoeva Anastasiya Atanasova, Wollina Uwe, Lotti Torello, Wilson Barbara B

机构信息

School of Medicine, University of Virginia Health System, Charlottesville, VA, USA.

Department of Dermatology, University of Virginia Health System, Charlottesville, VA, USA.

出版信息

Wien Med Wochenschr. 2017 Mar;167(3-4):74-77. doi: 10.1007/s10354-016-0525-3. Epub 2016 Nov 10.

Abstract

A 67-year-old woman presented with a firm plaque in the perineal region, 16 months after diagnosis of a high-grade basaloid squamous cell carcinoma of the vagina and treatment by external beam radiation therapy and vaginal cuff brachytherapy. The differential diagnosis included radiation-induced morphea, radiation dermatitis, or, possibly, radiation-induced lichen sclerosus. Biopsy findings, including special staining, confirmed the diagnosis of radiation-induced lichen sclerosus. To our knowledge, this is the first report of radiation-induced lichen sclerosus of the vulvar region.

摘要

一名67岁女性在被诊断为阴道高级别基底样鳞状细胞癌并接受体外放射治疗和阴道袖口近距离放射治疗16个月后,会阴部出现一个硬结性斑块。鉴别诊断包括放射性硬皮病、放射性皮炎,或者可能是放射性苔藓硬化症。活检结果,包括特殊染色,证实为放射性苔藓硬化症。据我们所知,这是外阴部放射性苔藓硬化症的首例报告。

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