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芬兰异位妊娠率的上升——时间效应与队列效应的综合影响

Increase of ectopic pregnancy in Finland--combination of time and cohort effects.

作者信息

Mäkinen J I

机构信息

Department of Obstetrics and Gynecology, University Central Hospital of Turku, Finland.

出版信息

Obstet Gynecol. 1989 Jan;73(1):21-4.

PMID:2783261
Abstract

The marked increase of ectopic pregnancy in Finland was studied in 5-year age groups from 1968-1984. In the early 1970s, the overall increase was attributable to women under 30 years of age, and in the early 1980s to women aged 30 years or more. The increase in the incidence rate of ectopic pregnancy per 100,000 women has taken place somewhat successively since the late 1960s in women aged 20-24, 25-29, 30-34, and 35-39 years. The incidence of ectopic pregnancy per 100,000 women increased by every successive 5-year cohort born since the late 1930s up to the cohort born in 1954-1958; thereafter, the birth cohorts have experienced an equal or even lower risk of ectopic pregnancy. The findings suggest that the large "baby boom" cohort (born in 1945-1954), with its high risk of ectopic pregnancy, is mainly responsible for the overall increase in the number of ectopic pregnancies seen in the past decade. When these cohorts end their reproductive years, the marked increase in the number of ectopic pregnancies in Finland may decrease, but the incidence rates will probably stay stable.

摘要

对1968年至1984年期间芬兰异位妊娠显著增加的情况按5岁年龄组进行了研究。20世纪70年代初,总体增加归因于30岁以下的女性,而在80年代初则归因于30岁及以上的女性。自20世纪60年代末以来,每10万名20至24岁、25至29岁、30至34岁和35至39岁女性的异位妊娠发病率有所相继上升。自20世纪30年代末以来,每10万名女性中异位妊娠的发病率在每一个相继出生的5年队列中都有所增加,直至1954年至1958年出生的队列;此后,出生队列的异位妊娠风险相等甚至更低。研究结果表明,具有高异位妊娠风险的“婴儿潮”大群体(出生于1945年至1954年)是过去十年中异位妊娠病例总数总体增加的主要原因。当这些队列结束其生育年龄时,芬兰异位妊娠病例数的显著增加可能会减少,但发病率可能会保持稳定。

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