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“阿育吠陀图尔西济万加”油缓解慢性肌肉骨骼疼痛的治疗评估

Therapeutic evaluation of "Ayush Tulsi Jiwan Plus" oil for chronic musculoskeletal pain relief.

作者信息

Sharma Kunal, Sahoo Jagannath, Sahu Dipsundar, Chattopadhyay Abichal, Kumar Sanjay, Mishra Sudhanshu Sekhar

机构信息

Department of Pharmacology, IMS and SUM Hospital, SOA University, Bhubaneswar, Odisha, India.

Department of Orthopaedics, IMS and SUM Hospital, SOA University, Bhubaneswar, Odisha, India.

出版信息

Ayu. 2015 Oct-Dec;36(4):387-396. doi: 10.4103/0974-8520.190687.

Abstract

BACKGROUND

Chronic pain of musculoskeletal origin is a very common symptom and has major effect on the physical, mental, and economic aspects of the patients. There is always a crave among physicians and patients for effective analgesic, curable preparation that can be locally applied.

AIM

The aim of this study is to assess the efficacy and safety of "Ayush Tulsi Jiwan Plus" oil in chronic pain management of musculoskeletal origin.

MATERIALS AND METHODS

Fifty patients of chronic musculoskeletal pain of unknown origin of mild to moderate condition were advised to apply "Ayush Tulsi Jiwan Plus" oil locally twice daily for 6 weeks and examined weekly. After completion of the treatment, the efficacy of the therapy was assessed on the basis of the subjective criteria such as perception of pain, tenderness, swelling, and joint mobility.

RESULTS

In this study, mean baseline score versus last visit score of pain (2.84 ± 0.68 vs. 1.33 ± 0.76), tenderness (1.64 ± 0.74 vs. 0.36 ± 0.56), and swelling (0.64 ± 0.85 vs. 0.38 ± 0.66) was significantly decreased, and also clinical improvement was seen in the study participants along with no evidence of adverse drug reactions.

CONCLUSION

The analysis of the overall effect of this "Ayush Tulsi Jiwan Plus" oil preparation was found efficacious and topically safe in chronic pain conditions. However, further study will be required with larger sample size and in heterogeneous population to elicit long-term effect of this polyherbal preparation.

摘要

背景

肌肉骨骼源性慢性疼痛是一种非常常见的症状,对患者的身体、心理和经济方面都有重大影响。医生和患者一直渴望有可局部应用的有效镇痛、可治愈的制剂。

目的

本研究的目的是评估“阿育吠陀图尔西吉万加”油在肌肉骨骼源性慢性疼痛管理中的疗效和安全性。

材料与方法

50例轻度至中度不明原因的慢性肌肉骨骼疼痛患者被建议每天在局部使用两次“阿育吠陀图尔西吉万加”油,持续6周,并每周进行检查。治疗完成后,根据疼痛、压痛、肿胀和关节活动度等主观标准评估治疗效果。

结果

在本研究中,疼痛的平均基线评分与末次访视评分(2.84±0.68对1.33±0.76)、压痛(1.64±0.74对0.36±0.56)和肿胀(0.64±0.85对0.38±0.66)显著降低,研究参与者的临床症状也有所改善,且无药物不良反应的证据。

结论

“阿育吠陀图尔西吉万加”油制剂的总体效果分析表明,其在慢性疼痛情况下有效且局部安全。然而,需要进一步开展更大样本量和不同人群的研究,以明确这种多草药制剂的长期效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f585/5041386/3075323bae11/AYU-36-387-g005.jpg

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