• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

HDBR Expression: A Unique Resource for Global and Individual Gene Expression Studies during Early Human Brain Development.

作者信息

Lindsay Susan J, Xu Yaobo, Lisgo Steven N, Harkin Lauren F, Copp Andrew J, Gerrelli Dianne, Clowry Gavin J, Talbot Aysha, Keogh Michael J, Coxhead Jonathan, Santibanez-Koref Mauro, Chinnery Patrick F

机构信息

Institute of Genetic Medicine, Newcastle University Newcastle upon Tyne, UK.

Institute of Genetic Medicine, Newcastle UniversityNewcastle upon Tyne, UK; Institute of Neuroscience, Newcastle UniversityNewcastle upon Tyne, UK.

出版信息

Front Neuroanat. 2016 Oct 26;10:86. doi: 10.3389/fnana.2016.00086. eCollection 2016.

DOI:10.3389/fnana.2016.00086
PMID:27833533
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5080337/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6758/5080337/0d7e43edb8d3/fnana-10-00086-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6758/5080337/0d7e43edb8d3/fnana-10-00086-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6758/5080337/0d7e43edb8d3/fnana-10-00086-g0001.jpg

相似文献

1
HDBR Expression: A Unique Resource for Global and Individual Gene Expression Studies during Early Human Brain Development.卧床休息模拟研究中的基因表达：人类早期大脑发育过程中全球和个体基因表达研究的独特资源。
Front Neuroanat. 2016 Oct 26;10:86. doi: 10.3389/fnana.2016.00086. eCollection 2016.
2
Effects of Spaceflight Stressors on Brain Volume, Microstructure, and Intracranial Fluid Distribution.太空飞行应激源对脑容量、微观结构和颅内液体分布的影响。
Cereb Cortex Commun. 2021 Mar 30;2(2):tgab022. doi: 10.1093/texcom/tgab022. eCollection 2021.
3
Enabling research with human embryonic and fetal tissue resources.利用人类胚胎和胎儿组织资源开展研究。
Development. 2015 Sep 15;142(18):3073-6. doi: 10.1242/dev.122820.
4
Visuomotor Adaptation Brain Changes During a Spaceflight Analog With Elevated Carbon Dioxide (CO): A Pilot Study.视觉运动适应大脑变化在一个空间飞行模拟与升高的二氧化碳（CO）：一项初步研究。
Front Neural Circuits. 2021 Jun 7;15:659557. doi: 10.3389/fncir.2021.659557. eCollection 2021.
5
Increased Brain Activation for Dual Tasking with 70-Days Head-Down Bed Rest.70天头低位卧床休息后执行双重任务时大脑激活增加。
Front Syst Neurosci. 2016 Aug 23;10:71. doi: 10.3389/fnsys.2016.00071. eCollection 2016.
6
Exercise effects on bed rest-induced brain changes.运动对卧床休息引起的大脑变化的影响。
PLoS One. 2018 Oct 11;13(10):e0205515. doi: 10.1371/journal.pone.0205515. eCollection 2018.
7
Brain Microstructure and Brain Function Changes in Space Headache by Head-Down-Tilted Bed Rest.卧床头低位倾斜对空间性头痛患者的脑微观结构和脑功能的影响。
Aerosp Med Hum Perform. 2023 Sep 1;94(9):678-685. doi: 10.3357/AMHP.6177.2023.
8
The effect of exercise training on left ventricular relaxation and diastolic suction at rest and during orthostatic stress after bed rest.运动训练对卧床休息后直立应激时左心室舒张松弛和舒张抽吸的影响。
Exp Physiol. 2013 Feb;98(2):501-13. doi: 10.1113/expphysiol.2012.067488. Epub 2012 Sep 21.
9
Artificial gravity during a spaceflight analog alters brain sensory connectivity.太空飞行模拟中的人工重力改变了大脑的感觉连通性。
Neuroimage. 2023 Sep;278:120261. doi: 10.1016/j.neuroimage.2023.120261. Epub 2023 Jul 6.
10
Brain connectivity and behavioral changes in a spaceflight analog environment with elevated CO.高浓度 CO 环境下的空间飞行模拟对大脑连接和行为变化的影响。
Neuroimage. 2021 Jan 15;225:117450. doi: 10.1016/j.neuroimage.2020.117450. Epub 2020 Oct 16.

引用本文的文献

1
Identification of a Novel GRM1 Frameshift Variant in Two Pakistani Families Broadens the Genetic Landscape of Ultra-Rare Spinocerebellar Ataxia Type 13.在两个巴基斯坦家庭中鉴定出一种新型GRM1移码变异，拓宽了超罕见13型脊髓小脑共济失调的遗传谱。
Cerebellum. 2025 Aug 27;24(5):145. doi: 10.1007/s12311-025-01897-w.
2
Early establishment and life course stability of sex biases in the human brain transcriptome.人类大脑转录组中性别偏见的早期确立及生命历程稳定性
Cell Genom. 2025 Jul 9;5(7):100890. doi: 10.1016/j.xgen.2025.100890. Epub 2025 May 26.
3
Narrow Versus Broad Phenotype Definitions Affect Genetic Analysis of Language More Than Other Broad Autism Phenotype Traits.

本文引用的文献

1
Enabling research with human embryonic and fetal tissue resources.利用人类胚胎和胎儿组织资源开展研究。
Development. 2015 Sep 15;142(18):3073-6. doi: 10.1242/dev.122820.
2
A survey of human brain transcriptome diversity at the single cell level.单细胞水平上人类大脑转录组多样性的一项调查。
Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7285-90. doi: 10.1073/pnas.1507125112. Epub 2015 May 18.
3
Evolutionary genomics. Evolutionary changes in promoter and enhancer activity during human corticogenesis.进化基因组学。人类皮质发生过程中启动子和增强子活性的进化变化。
与其他广泛的自闭症表型特征相比，狭义与广义表型定义对语言遗传分析的影响更大。
Res Sq. 2025 May 6:rs.3.rs-5457750. doi: 10.21203/rs.3.rs-5457750/v1.
4
Transcriptomic sex differences in early human fetal brain development.人类早期胎儿大脑发育中的转录组性别差异。
Commun Biol. 2025 Apr 25;8(1):664. doi: 10.1038/s42003-025-08070-3.
5
The Gene Family: Underexplored Yet Essential Mediators of Oxidative Stress.基因家族：未被充分探索却至关重要的氧化应激介质
Biomolecules. 2025 Mar 13;15(3):409. doi: 10.3390/biom15030409.
6
Genome-wide screening reveals essential roles for HOX genes and imprinted genes during caudal neurogenesis of human embryonic stem cells.全基因组筛选揭示了 HOX 基因和印迹基因在人胚胎干细胞尾部神经发生过程中的重要作用。
Stem Cell Reports. 2024 Nov 12;19(11):1598-1619. doi: 10.1016/j.stemcr.2024.09.009. Epub 2024 Oct 31.
7
DNA methylation shapes the Polycomb landscape during the exit from naive pluripotency.在从幼稚多能性退出的过程中，DNA甲基化塑造了多梳蛋白景观。
Nat Struct Mol Biol. 2025 Feb;32(2):346-357. doi: 10.1038/s41594-024-01405-4. Epub 2024 Oct 24.
8
Disruption of common ocular developmental pathways in patient-derived optic vesicle models of microphthalmia.患者来源的小眼球视囊模型中常见眼部发育途径的破坏。
Stem Cell Reports. 2024 Jun 11;19(6):839-858. doi: 10.1016/j.stemcr.2024.05.001. Epub 2024 May 30.
9
Cross-ancestry atlas of gene, isoform, and splicing regulation in the developing human brain.跨种族人类大脑发育过程中基因、异构体和剪接调控的图谱
Science. 2024 May 24;384(6698):eadh0829. doi: 10.1126/science.adh0829.
10
Severe Neurodevelopmental Disorder in Autosomal Recessive Spinocerebellar Ataxia 13 (SCAR13) Caused by Two Novel Frameshift Variants in GRM1.常染色体隐性遗传脊髓小脑共济失调 13 型（SCAR13）中严重神经发育障碍是由 GRM1 中的两个新的移码变异引起的。
Cerebellum. 2024 Oct;23(5):1768-1771. doi: 10.1007/s12311-023-01617-2. Epub 2023 Oct 13.
Science. 2015 Mar 6;347(6226):1155-9. doi: 10.1126/science.1260943.
4
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2.使用DESeq2对RNA测序数据的倍数变化和离散度进行适度估计。
Genome Biol. 2014;15(12):550. doi: 10.1186/s13059-014-0550-8.
5
ArrayExpress update--simplifying data submissions.ArrayExpress更新——简化数据提交
Nucleic Acids Res. 2015 Jan;43(Database issue):D1113-6. doi: 10.1093/nar/gku1057. Epub 2014 Oct 31.
6
Decoding neural transcriptomes and epigenomes via high-throughput sequencing.通过高通量测序解码神经转录组和表观基因组。
Nat Neurosci. 2014 Nov;17(11):1463-75. doi: 10.1038/nn.3814. Epub 2014 Oct 28.
7
HTSeq--a Python framework to work with high-throughput sequencing data.HTSeq——一个用于处理高通量测序数据的Python框架。
Bioinformatics. 2015 Jan 15;31(2):166-9. doi: 10.1093/bioinformatics/btu638. Epub 2014 Sep 25.
8
Transcriptional landscape of the prenatal human brain.人类产前大脑的转录组图谱。
Nature. 2014 Apr 10;508(7495):199-206. doi: 10.1038/nature13185. Epub 2014 Apr 2.
9
Expression Atlas update--a database of gene and transcript expression from microarray- and sequencing-based functional genomics experiments.Expression Atlas 更新——一个基于微阵列和测序的功能基因组学实验的基因和转录本表达数据库。
Nucleic Acids Res. 2014 Jan;42(Database issue):D926-32. doi: 10.1093/nar/gkt1270. Epub 2013 Dec 4.
10
TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions.TopHat2：在存在插入、缺失和基因融合的情况下对转录组进行精确比对。
Genome Biol. 2013 Apr 25;14(4):R36. doi: 10.1186/gb-2013-14-4-r36.