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来自西藏铁筷子的新的小螺甾烷醇糖苷。

New minor spirostanol glycosides from Helleborus thibetanus.

作者信息

Zhang Hui, Su Yan-Fang, Yang Feng-Ying, Gao Xiu-Mei

机构信息

a Tianjin Key Laboratory for Modern Drug Delivery and High-Efficiency, School of Pharmaceutical Science and Technology , Tianjin University , Tianjin , P.R. China.

b School of Pharmaceutical Science and Technology , Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) , Tianjin , P.R. China.

出版信息

Nat Prod Res. 2017 Apr;31(8):925-931. doi: 10.1080/14786419.2016.1255888. Epub 2016 Nov 11.

Abstract

Phytochemical reinvestigation of the dried roots and rhizomes of Helleborus thibetanus afforded four new minor spirostanol glycosides (1-4) and four known spirostanol glycosides (5-8). Their structures were determined on the basis of spectroscopic analyses, including 1D and 2D NMR experiments, together with HR-ESI-MS and IR measurements and the results of acid hydrolysis.

摘要

对太白铁线莲干燥根及根茎进行植物化学再研究,得到了4个新的微量螺旋甾烷醇苷(1 - 4)和4个已知的螺旋甾烷醇苷(5 - 8)。它们的结构是基于光谱分析确定的,包括一维和二维核磁共振实验,以及高分辨电喷雾电离质谱和红外测量,还有酸水解的结果。

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