Caplan Michael S, Fanaroff Avroy
Department of Pediatrics, Chief Scientific Officer, Northshore University, Healthsystem, Clinical Professor of Pediatrics, University of Chicago, Pritzker School of Medicine.
Eliza Henry Barnes chair in Neonatology, Rainbow Babies and Children's Hospital.
Semin Perinatol. 2017 Feb;41(1):2-6. doi: 10.1053/j.semperi.2016.09.012. Epub 2016 Nov 8.
Necrotizing enterocolitis is a devastating disease afflicting premature infants, though after 50 years of investigation, the pathophysiology remains elusive. This report describes the possible etiologic factors from a historical perspective, and outlines the importance of human milk, intestinal blood flow, and intestinal blood flow changes from a developmental perspective over the last 40-50 years.
坏死性小肠结肠炎是一种侵袭早产儿的毁灭性疾病,尽管经过50年的研究,其病理生理学仍不清楚。本报告从历史角度描述了可能的病因,并从发育角度概述了过去40 - 50年中母乳、肠血流及肠血流变化的重要性。