Welty Stephen E
Department of Pediatrics, Baylor College of Medicine, 6621 Fannin Street, W1604, Houston, TX 77030, USA.
Clin Perinatol. 2016 Dec;43(4):661-671. doi: 10.1016/j.clp.2016.07.004.
Premature neonates are predisposed to complications, including bronchopulmonary dysplasia (BPD). BPD is associated with long-term pulmonary and neurodevelopmental consequences. Noninvasive respiratory support with nasal continuous positive airway pressure (CPAP) has been recommended strongly by the American Academy of Pediatrics. However, CPAP implementation has shown at least a 50% failure rate. Enhancing nasal CPAP effectiveness may decrease the need for mechanical ventilation and reduce the incidence of BPD. Bubble nasal CPAP is better than nasal CPAP using mechanical devices and the bubbling provides air exchange in distal respiratory units. The Seattle PAP system reduces parameters that assess work of breathing.
早产新生儿易发生并发症，包括支气管肺发育不良（BPD）。BPD与长期肺部和神经发育后果相关。美国儿科学会强烈推荐使用经鼻持续气道正压通气（CPAP）进行无创呼吸支持。然而，CPAP的实施显示至少有50%的失败率。提高经鼻CPAP的有效性可能会减少机械通气的需求并降低BPD的发生率。气泡式经鼻CPAP比使用机械设备的经鼻CPAP更好，并且气泡可在远端呼吸单位进行气体交换。西雅图PAP系统降低了评估呼吸功的参数。
