Hassoon Ahmed, Bydon Mohamad, Kerezoudis Panagiotis, Maloney Patrick R, Rinaldo Lorenzo, Yeh Hsin-Chieh
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, Baltimore, MD 21205, USA.
Department of Neurosurgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
J Diabetes Complications. 2017 Jan;31(1):38-42. doi: 10.1016/j.jdiacomp.2016.10.025. Epub 2016 Oct 24.
The aim of this study was to test the hypothesis that diabetes mellitus (DM) is associated with an increased prevalence of chronic low back pain (CLBP) in the general population. We analyzed data for 5106 adults (4591 without DM & 515 with diagnosed DM), who were part of the National Health and Nutrition Examination Survey (NHANES) from 2009 through 2010. Adults with DM were older (mean age 54.2years' vs. 42.1years), more likely to be obese (BMI>30, 69.5% vs. 33.3%), less educated (college or above 44.4% vs. 57.3%), had a lower annual income (<$20,000, 16.8% vs. 13.4%), were more likely to be a former smoker (31.5% vs. 20.9%), less physically active (43.5% vs. 59.4%). The prevalence of CLBP was 19.8% in adults with DM vs. 12.9% in adults without DM (age-adjusted OR 1.46; 95% CI, 1.00-1.94, P=.050). After the adjustments for CLBP's known risk factors, the association remained significant (OR 1.39; 95% CI, 1.02-1.92, P=.041). Adults with DM have a higher prevalence of CLBP. Further research is needed to examine the association and pathophysiology of DM and CLBP as well as the role of shared risk factors.
Adults with diabetes have higher prevalence of chronic low back pain (CLBP), and higher odds of CLBP after adjusting for LBP risk factors.
本研究的目的是检验糖尿病（DM）与普通人群中慢性腰痛（CLBP）患病率增加相关这一假设。我们分析了2009年至2010年美国国家健康与营养检查调查（NHANES）中的5106名成年人的数据（4591名无糖尿病者和515名已确诊糖尿病者）。患有糖尿病的成年人年龄更大（平均年龄54.2岁对42.1岁），更有可能肥胖（体重指数>30，69.5%对33.3%），受教育程度较低（大学及以上学历44.4%对57.3%），年收入较低（<20,000美元，16.8%对13.4%），更有可能是既往吸烟者（31.5%对20.9%），身体活动较少（43.5%对59.4%）。糖尿病成年人中CLBP的患病率为19.8%，无糖尿病成年人中为12.9%（年龄调整后的比值比1.46；95%置信区间，1.00 - 1.94，P = 0.050）。在对CLBP的已知危险因素进行调整后，这种关联仍然显著（比值比1.39；95%置信区间，1.02 - 1.92，P = 0.041）。患有糖尿病的成年人CLBP患病率更高。需要进一步研究以探讨糖尿病与CLBP之间的关联和病理生理学以及共同危险因素的作用。
患有糖尿病的成年人慢性腰痛（CLBP）患病率更高，在调整腰痛危险因素后患CLBP的几率也更高。
