Attanasio Giuseppe, Cagnoni Laura, Masci Eleonora, Ciciarello Francesco, Diaferia Francesco, Bruno Aldo, Greco Antonio, De Vincentiis Marco
a Head and Neck Department , Umberto I Polyclinic of Rome , Italy.
b Department of Sense Organs , Sapienza University of Rome , Italy.
Acta Otolaryngol. 2017 May;137(5):460-463. doi: 10.1080/00016489.2016.1252853. Epub 2016 Nov 16.
The present study confirms a correlation between chronic cerebrospinal venous insufficiency (CCSVI) diagnosis and Ménière's disease (MD). CCSVI could be considered a new ultrasound vascular pattern of the cerebrospinal venous system in patients affected by definite MD. Conversely, the present results showed that CCSVI cannot be considered a pathogenic mechanism for idiopathic sudden sensorineural hearing loss (ISSNHL).
The aim of this study is to investigate the correlation between CCSVI and MD and to evaluate if CCSVI can be considered a risk factor also for ISSNHL. Moreover, this study seeks to establish if, even with a different timing of onset and natural history, MD and ISSNHL may share a common pathogenic mechanism.
One hundred and eighty-two patients affected by definite MD, 60 patients affected by ISSNHL, and 100 healthy control patients were enrolled in this study. All subjects underwent an echo-color Doppler (ECD) of the cerebrospinal venous flow.
One hundred and fifty-two patients affected by definite MD (83,5%) and 13 patients affected by ISSNHL (21.6%) were positive for CCSVI at the ECD examination of the cerebrospinal venous flow. The healthy control group consisted of 100 subjects and only 21 (21%) showed positivity for CCSVI.
本研究证实慢性脑脊髓静脉功能不全（CCSVI）诊断与梅尼埃病（MD）之间存在关联。CCSVI可被视为确诊MD患者脑脊髓静脉系统一种新的超声血管模式。相反，目前结果表明，CCSVI不能被视为特发性突发性感音神经性听力损失（ISSNHL）的致病机制。
本研究旨在调查CCSVI与MD之间的相关性，并评估CCSVI是否也可被视为ISSNHL的危险因素。此外，本研究试图确定，即使发病时间和自然病史不同，MD和ISSNHL是否可能有共同的致病机制。
本研究纳入了182例确诊MD患者、60例ISSNHL患者和100例健康对照者。所有受试者均接受了脑脊髓静脉血流的彩色多普勒超声（ECD）检查。
在脑脊髓静脉血流的ECD检查中，152例确诊MD患者（83.5%）和13例ISSNHL患者（21.6%）CCSVI呈阳性。健康对照组由100名受试者组成，只有21例（21%）CCSVI呈阳性。
