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中国西南部云南省越南人群20个常染色体STR基因座的遗传多态性。

Genetic polymorphisms of 20 autosomal STR loci in the Vietnamese population from Yunnan Province, Southwest China.

作者信息

Zhang Xiufeng, Hu Liping, Du Lei, Nie Aiting, Rao Min, Pang Jing Bo, Nie Shengjie

机构信息

School of Forensic Medicine, Kunming Medical University, Kunming, Yunnan Province, People's Republic of China, 650500.

Chenggong Public Security Bureau, Kunming, Yunnan Province, People's Republic of China.

出版信息

Int J Legal Med. 2017 May;131(3):661-662. doi: 10.1007/s00414-016-1496-z. Epub 2016 Nov 16.

DOI:10.1007/s00414-016-1496-z
PMID:27853877
Abstract

The genetic polymorphisms of 20 autosomal short tandem repeat (STR) loci included in the PowerPlex® 21 kit were evaluated in 522 healthy unrelated Vietnamese from Yunnan, China. All of the loci reached the Hardy-Weinberg equilibrium. These loci were examined to determine allele frequencies and forensic statistical parameters. The combined discrimination power and probability of excluding paternity of the 20 STR loci were 0.999999999999999999999991 26 and 0.999999975, respectively. Results suggested that the 20 STR loci are highly polymorphic, which is suitable for forensic personal identification and paternity testing.

摘要

对来自中国云南的522名健康无亲缘关系的越南人,评估了PowerPlex® 21试剂盒中包含的20个常染色体短串联重复序列(STR)位点的基因多态性。所有位点均达到哈迪-温伯格平衡。对这些位点进行检测以确定等位基因频率和法医学统计参数。20个STR位点的联合鉴别力和排除父权概率分别为0.999999999999999999999991 26和0.999999975。结果表明,这20个STR位点具有高度多态性,适用于法医学个人识别和亲子鉴定。

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