Yang Luyu, Zhang Xiufeng, Zhao Lijuan, Sun Yanan, Li Jiajue, Huang Renwu, Hu Liping, Nie Shengjie
School of Forensic Medicine, Kunming Medical University, Kunming, Yunnan Province, People's Republic of China.
Guangdong Huaxia Forensic Institute of Judicial Expertise, Guangzhou, Guangdong Province, People's Republic of China.
Int J Legal Med. 2018 Jan;132(1):133-135. doi: 10.1007/s00414-017-1588-4. Epub 2017 Apr 22.
The genetic polymorphisms of 23 autosomal short tandem repeat (STR) loci included in the HuaxiaTM Platinum kit were evaluated in 1533 unrelated healthy Guangdong Han individuals living in the Guangdong Province in southern China. All of the loci reached the Hardy-Weinberg equilibrium. These loci were examined to determine the allele frequencies and forensic statistical parameters. The genetic relationship between the Guangdong Han and other Chinese populations was also estimated. The combined discrimination power and the probability of excluding the paternity of 23 STR loci were 0.999 999 999 999 999 999 999 999 999 74 and 0.999 999 999 72, respectively. These results suggested that the 23 STR loci are highly polymorphic and suitable for personal forensic identification and paternity testing.
对华夏TM铂金试剂盒中包含的23个常染色体短串联重复序列（STR）位点的基因多态性，在中国南方广东省的1533名无亲缘关系的健康广东汉族个体中进行了评估。所有位点均达到哈迪-温伯格平衡。检测这些位点以确定等位基因频率和法医学统计参数。还估计了广东汉族与其他中国人群之间的遗传关系。23个STR位点的联合鉴别力和排除父权的概率分别为0.999 999 999 999 999 999 999 999 999 74和0.999 999 999 72。这些结果表明，这23个STR位点具有高度多态性，适用于个人法医学鉴定和亲子鉴定。
