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从马来西亚分离出的携带CTX-M-65的两株多重耐药奇异变形杆菌的基因组序列

Genome Sequences of Two Multidrug-Resistant Proteus mirabilis Strains Harboring CTX-M-65 Isolated from Malaysia.

作者信息

Yu Choo Yee, Ang Geik Yong, Ngeow Yun Fong, Tee Kok Keng, Yin Wai-Fong, Chan Kok-Gan

机构信息

Division of Genetics and Molecular Biology, Institute of Biological Sciences, University of Malaya, Kuala Lumpur, Malaysia.

Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA, Kuala Lumpur, Malaysia.

出版信息

Genome Announc. 2016 Nov 17;4(6):e01301-16. doi: 10.1128/genomeA.01301-16.

DOI:10.1128/genomeA.01301-16
PMID:27856593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5114385/
Abstract

Proteus mirabilis is an opportunistic nosocomial pathogen that is commonly associated with urinary tract infections. Here, we present draft genome sequences of two multidrug-resistant P. mirabilis strains, isolated from urine samples in Malaysia, that harbored a CTX-M-type extended-spectrum β-lactamase-encoding gene, as well as a repertoire of other antimicrobial-resistant determinants.

摘要

奇异变形杆菌是一种机会性医院病原体，通常与尿路感染有关。在此，我们展示了从马来西亚尿液样本中分离出的两株耐多药奇异变形杆菌菌株的基因组草图序列，这些菌株携带一个CTX-M型超广谱β-内酰胺酶编码基因以及一系列其他抗微生物耐药决定因素。

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本文引用的文献

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Proteus mirabilis urinary tract infection and bacteremia: risk factors, clinical presentation, and outcomes.奇异变形杆菌尿路感染和菌血症：危险因素、临床表现和结局。
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Multidrug-resistant Proteus mirabilis bloodstream infections: risk factors and outcomes.多重耐药奇异变形杆菌血流感染：危险因素和结局。
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The RAST Server: rapid annotations using subsystems technology.RAST服务器：使用子系统技术进行快速注释。
BMC Genomics. 2008 Feb 8;9:75. doi: 10.1186/1471-2164-9-75.
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Proteus mirabilis bloodstream infections: risk factors and treatment outcome related to the expression of extended-spectrum beta-lactamases.奇异变形杆菌血流感染：与超广谱β-内酰胺酶表达相关的危险因素及治疗结果
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Classification, identification, and clinical significance of Proteus, Providencia, and Morganella.变形杆菌属、普罗威登斯菌属和摩根菌属的分类、鉴定及临床意义
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