• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Genetically modified human umbilical cord blood cells as a promising strategy for treatment of spinal cord injury.

作者信息

Mukhamedshina Yana O, Rizvanov Albert A

机构信息

Kazan (Volga Region) Federal University, Kazan, Russia.

出版信息

Neural Regen Res. 2016 Sep;11(9):1420-1421. doi: 10.4103/1673-5374.191213.

DOI:10.4103/1673-5374.191213
PMID:27857742
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5090841/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d19/5090841/f4d9c186bfcd/NRR-11-1420-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d19/5090841/f6ea63fcb1cb/NRR-11-1420-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d19/5090841/f4d9c186bfcd/NRR-11-1420-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d19/5090841/f6ea63fcb1cb/NRR-11-1420-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d19/5090841/f4d9c186bfcd/NRR-11-1420-g002.jpg

相似文献

1
Genetically modified human umbilical cord blood cells as a promising strategy for treatment of spinal cord injury.基因改造的人脐带血细胞作为治疗脊髓损伤的一种有前景的策略。
Neural Regen Res. 2016 Sep;11(9):1420-1421. doi: 10.4103/1673-5374.191213.
2
Influence of Genetically Modified Human Umbilical Cord Blood Mononuclear Cells on the Expression of Schwann Cell Molecular Determinants in Spinal Cord Injury.转基因人脐带血单个核细胞对脊髓损伤中雪旺细胞分子决定因素表达的影响。
Stem Cells Int. 2018 Feb 18;2018:4695275. doi: 10.1155/2018/4695275. eCollection 2018.
3
Functional recovery in acute traumatic spinal cord injury after transplantation of human umbilical cord mesenchymal stem cells.人脐带间充质干细胞移植治疗急性创伤性脊髓损伤的功能恢复。
Crit Care Med. 2010 Nov;38(11):2181-9. doi: 10.1097/CCM.0b013e3181f17c0e.
4
Collagen scaffold combined with human umbilical cord-mesenchymal stem cells transplantation for acute complete spinal cord injury.胶原蛋白支架联合人脐带间充质干细胞移植治疗急性完全性脊髓损伤。
Neural Regen Res. 2020 Sep;15(9):1686-1700. doi: 10.4103/1673-5374.276340.
5
[Transplantation of human umbilical cord stem cells improves neurological function recovery after spinal cord injury in rats].人脐带干细胞移植改善大鼠脊髓损伤后神经功能恢复
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2004 Feb;26(1):38-42.
6
Assessment of Glial Scar, Tissue Sparing, Behavioral Recovery and Axonal Regeneration following Acute Transplantation of Genetically Modified Human Umbilical Cord Blood Cells in a Rat Model of Spinal Cord Contusion.在大鼠脊髓挫伤模型中急性移植基因修饰的人脐带血细胞后对胶质瘢痕、组织保留、行为恢复和轴突再生的评估
PLoS One. 2016 Mar 22;11(3):e0151745. doi: 10.1371/journal.pone.0151745. eCollection 2016.
7
Evaluation of direct and cell-mediated triple-gene therapy in spinal cord injury in rats.大鼠脊髓损伤中直接和细胞介导的三基因疗法评估
Brain Res Bull. 2017 Jun;132:44-52. doi: 10.1016/j.brainresbull.2017.05.005. Epub 2017 May 18.
8
Human umbilical cord blood stem cells infusion in spinal cord injury: engraftment and beneficial influence on behavior.人脐带血干细胞输注治疗脊髓损伤：植入及对行为的有益影响
J Hematother Stem Cell Res. 2003 Jun;12(3):271-8. doi: 10.1089/152581603322023007.
9
Genetically modified Schwann cells producing glial cell line-derived neurotrophic factor inhibit neuronal apoptosis in rat spinal cord injury.产生胶质细胞源性神经营养因子的转基因雪旺细胞可抑制大鼠脊髓损伤中的神经元凋亡。
Mol Med Rep. 2014 Apr;9(4):1305-12. doi: 10.3892/mmr.2014.1963. Epub 2014 Feb 18.
10
Repeated injections of human umbilical cord blood-derived mesenchymal stem cells significantly promotes functional recovery in rabbits with spinal cord injury of two noncontinuous segments.重复注射人脐带血源间充质干细胞显著促进了两段不连续脊髓损伤兔的功能恢复。
Stem Cell Res Ther. 2018 May 11;9(1):136. doi: 10.1186/s13287-018-0879-0.

引用本文的文献

1
Application of a New Gene-Cell Construct Based on the Olfactory Mucosa Escheating Cells Transduced with an Adenoviral Vector Encoding Mature BDNF in the Therapy of Spinal Cord Cysts.基于转导腺病毒载体编码成熟 BDNF 的嗅黏膜废弃细胞的新型基因细胞构建物在脊髓囊肿治疗中的应用。
Bull Exp Biol Med. 2022 Mar;172(5):617-621. doi: 10.1007/s10517-022-05446-x. Epub 2022 Mar 30.
2
Gene-modified leucoconcentrate for personalized gene therapy in a mini pig model of moderate spinal cord injury.基因修饰白细胞浓缩物用于中度脊髓损伤小型猪模型的个性化基因治疗。
Neural Regen Res. 2021 Feb;16(2):357-361. doi: 10.4103/1673-5374.290902.

本文引用的文献

1
Assessment of Glial Scar, Tissue Sparing, Behavioral Recovery and Axonal Regeneration following Acute Transplantation of Genetically Modified Human Umbilical Cord Blood Cells in a Rat Model of Spinal Cord Contusion.在大鼠脊髓挫伤模型中急性移植基因修饰的人脐带血细胞后对胶质瘢痕、组织保留、行为恢复和轴突再生的评估
PLoS One. 2016 Mar 22;11(3):e0151745. doi: 10.1371/journal.pone.0151745. eCollection 2016.
2
Adenoviral vector carrying glial cell-derived neurotrophic factor for direct gene therapy in comparison with human umbilical cord blood cell-mediated therapy of spinal cord injury in rat.携带胶质细胞源性神经营养因子的腺病毒载体用于直接基因治疗，与大鼠脊髓损伤的人脐带血细胞介导治疗的比较
Spinal Cord. 2016 May;54(5):347-59. doi: 10.1038/sc.2015.161. Epub 2015 Sep 29.
3
Cell Therapy Augments Functional Recovery Subsequent to Spinal Cord Injury under Experimental Conditions.在实验条件下，细胞疗法可增强脊髓损伤后的功能恢复。
Stem Cells Int. 2015;2015:132172. doi: 10.1155/2015/132172. Epub 2015 Jul 9.
4
Schwann cell-like remyelination following transplantation of human umbilical cord blood (hUCB)-derived mesenchymal stem cells in dogs with acute spinal cord injury.人脐带血源间充质干细胞移植后犬急性脊髓损伤的雪旺细胞样髓鞘再生。
J Neurol Sci. 2011 Jan 15;300(1-2):86-96. doi: 10.1016/j.jns.2010.09.025. Epub 2010 Nov 10.
5
Feasibility of combination allogeneic stem cell therapy for spinal cord injury: a case report.同种异体干细胞联合治疗脊髓损伤的可行性：一例报告
Int Arch Med. 2010 Nov 11;3:30. doi: 10.1186/1755-7682-3-30.
6
The effect of umbilical cord blood cells on outcomes after experimental traumatic spinal cord injury.脐带血细胞对实验性创伤性脊髓损伤后结局的影响。
Spine (Phila Pa 1976). 2010 Jul 15;35(16):1520-6. doi: 10.1097/BRS.0b013e3181c3e963.
7
Challenges of stem cell therapy for spinal cord injury: human embryonic stem cells, endogenous neural stem cells, or induced pluripotent stem cells?脊髓损伤干细胞治疗的挑战：人胚胎干细胞、内源性神经干细胞还是诱导多能干细胞？
Stem Cells. 2010 Jan;28(1):93-9. doi: 10.1002/stem.253.
8
Transplantation-mediated strategies to promote axonal regeneration following spinal cord injury.脊髓损伤后促进轴突再生的移植介导策略。
Respir Physiol Neurobiol. 2009 Nov 30;169(2):171-82. doi: 10.1016/j.resp.2009.07.016. Epub 2009 Aug 7.
9
Neuronal apoptosis is inhibited by cord blood stem cells after spinal cord injury.脊髓损伤后，脐血干细胞抑制神经元凋亡。
J Neurotrauma. 2009 Nov;26(11):2057-69. doi: 10.1089/neu.2008.0725.
10
Infusion of human umbilical cord blood cells ameliorates hind limb dysfunction in experimental spinal cord injury through anti-inflammatory, vasculogenic and neurotrophic mechanisms.输注人脐带血细胞通过抗炎、血管生成和神经营养机制改善实验性脊髓损伤中的后肢功能障碍。
Pediatr Neonatol. 2008 Jun;49(3):77-83. doi: 10.1016/S1875-9572(08)60017-0.