Perepelov Andrei V, Guo Xi, Senchenkova Sof'ya N, Shashkov Alexander S, Liu Bin, Knirel Yuriy A
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991, Moscow, Russian Federation.
Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, TEDA Institute of Biological Sciences and Biotechnology, Nankai University, TEDA, Tianjin, China.
Carbohydr Res. 2016 Dec 21;436:41-44. doi: 10.1016/j.carres.2016.11.003. Epub 2016 Nov 4.
The O-polysaccharide (O-antigen) of Escherichia coli O131 was studied by sugar analysis along with 1D and 2D H and C NMR spectroscopy. The following structure of the linear tetrasaccharide repeating unit of the polysaccharide was established: →8)-α-Neup5Ac-(2 → 6)-β-D-Galp-(1 → 6)-β-D-Galp-(1 → 3)-β-D-GalpNAc-(1→ The gene functions were tentatively assigned by comparison with sequences in the available databases and found to be in agreement with the E. coli O131-antigen structure.
通过糖分析以及一维和二维氢谱与碳谱核磁共振波谱对大肠杆菌O131的O-多糖（O-抗原）进行了研究。确定了该多糖线性四糖重复单元的以下结构：→8)-α-唾液酸-(2→6)-β-D-半乳糖-(1→6)-β-D-半乳糖-(1→3)-β-D-氨基半乳糖-(1→ 通过与现有数据库中的序列进行比较，初步确定了基因功能，发现其与大肠杆菌O131抗原结构一致。
