Okamoto T, Motohasi H, Takemiya S, Sugimasa Y, Sairenji M, Kobayasi S
Dept. of Surgery, Kanagawa Cancer Center Hospital.
Gan To Kagaku Ryoho. 1989 Apr;16(4 Pt 2-2):1533-7.
Juzen-daiho-to is one of the Chinese traditional medicines which is usually applied with patients suffering from anemia or chronic exhaustive disease. Twenty-three patients after gastrectomy and 16 patients after colectomy were studied for NK cell activity, blastogenesis by PHA, several T-lymphocyte subsets, serum triglyceride and serum lipo-protein before drug administration at one, three, six, nine months and one year after the start of drug administration respectively. A remarkable elevation in NK cell activity was noted 3 and 6 months after the drug administration. Statistical analysis shows a significant converse correlation between NK cell activity and lipo-protein value in the group given Juzendaiho-to.
十全大补汤是一种常用于贫血或慢性消耗性疾病患者的中药。分别对23例胃切除术后患者和16例结肠切除术后患者在给药前、给药开始后1个月、3个月、6个月、9个月及1年时进行自然杀伤（NK）细胞活性、PHA诱导的细胞增殖、几种T淋巴细胞亚群、血清甘油三酯和血清脂蛋白的研究。给药后3个月和6个月时观察到NK细胞活性显著升高。统计学分析显示，在给予十全大补汤的组中，NK细胞活性与脂蛋白值之间存在显著的负相关。
