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与膀胱癌细胞辅助性分枝杆菌治疗相关的关节炎。

Arthritis associated with adjuvant mycobacterial treatment for carcinoma of the bladder.

作者信息

Hughes R A, Allard S A, Maini R N

机构信息

Department of Immunology of Rheumatic Disease, Charing Cross Hospital, London.

出版信息

Ann Rheum Dis. 1989 May;48(5):432-4. doi: 10.1136/ard.48.5.432.

DOI:10.1136/ard.48.5.432
PMID:2786389
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1003777/
Abstract

A patient who developed an inflammatory polyarthritis following intravesical administration of bacillus Calmette-Guérin (BCG) used in the treatment of bladder cancer is described. An inflammatory synovitis comprising predominantly T lymphocytes was demonstrated on synovial biopsy. The synovitis resolved spontaneously within 14 days in this 'human model' of adjuvant arthritis.

摘要

本文描述了一名膀胱癌患者在膀胱内灌注卡介苗(BCG)后出现炎性多关节炎的情况。滑膜活检显示,炎症性滑膜炎主要由T淋巴细胞构成。在这个佐剂性关节炎的“人体模型”中,滑膜炎在14天内自行消退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/814f/1003777/d99df9be958d/annrheumd00427-0081-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/814f/1003777/d99df9be958d/annrheumd00427-0081-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/814f/1003777/d99df9be958d/annrheumd00427-0081-a.jpg

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PASSIVE TRANSFER OF ADJUVANT ARTHRITIS BY LYMPH NODE OR SPLEEN CELLS.佐剂性关节炎通过淋巴结或脾细胞的被动转移
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A reappraisal of the evidence that rheumatoid arthritis and several other idiopathic diseases are slow bacterial infections.对类风湿性关节炎和其他几种特发性疾病是慢性细菌感染这一证据的重新评估。
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Role of immunity to mycobacterial stress proteins in rheumatoid arthritis.分枝杆菌应激蛋白免疫在类风湿性关节炎中的作用。
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Prevention of adjuvant arthritis in rats by a nonapeptide from the 65-kD mycobacterial heat shock protein: specificity and mechanism.来自65-kD分枝杆菌热休克蛋白的九肽对大鼠佐剂性关节炎的预防作用:特异性及机制
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Arthritis induced in rats by cloned T lymphocytes responsive to mycobacteria but not to collagen type II.由对分枝杆菌有反应但对II型胶原无反应的克隆T淋巴细胞在大鼠中诱导产生的关节炎。
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