Gentile Ángela, Abate Héctor
Epidemiología, Hospital de Niños R. Gutiérrez, Ciudad Autónoma de Buenos Aires, Argentina.
Comité Regional para la Erradicación de la Poliomielitis, Ciudad Autónoma de Buenos Aires, Argentina.
Arch Argent Pediatr. 2016 Dec 1;114(6):557-562. doi: 10.5546/aap.2016.eng.557.
Poliovirus infects 100% of susceptible individuals and causes acute flaccid paralysis in one out of200 infections. Type 1 causes epidemic poliomyelitis; type 2 has been eradicated worldwide; and type 3 is close to being eradicated. In this region, the last case of wild poliovirus occurred in Peru in 1991. There are still two endemic countries: Afghanistan and Pakistan, but countries where there is no circulation of the wild poliovirus have also reported imported cases of polio. In May 2012, the World Health Assembly declared the polio eradication a programmatic emergency for global public health and, as a result, developed the Polio Eradication and Endgame Strategic Plan 2013-2018. The Plan has four objectives: 1) Detect and interrupt all poliovirus transmission and maintain surveillance of acute flaccid paralysis in children < 15 years. 2) Strengthen immunization systems and withdraw oral polio vaccine by the first trimester of 2016. Replace the trivalent oral polio vaccine with the bivalent oral vaccine, containing serotypes 1 and 3, and introduce the inactivated polio vaccine in all immunization schedules to maintain immunity against poliovirus type 2. 3) Contain poliovirus and certify interruption of transmission. 4) Plan the exploitation of the fight against polio and its impact on public health. The plan is expected to reach its goals by 2018; all use of the oral polio vaccine will be interrupted thereafter. Change in immunization schedules will require pediatricians to provide advice and guidance to families depending on the varied situations of everyday practice.
脊髓灰质炎病毒可感染100%的易感个体,每200次感染中会有1例导致急性弛缓性麻痹。1型病毒会引发脊髓灰质炎流行;2型病毒已在全球范围内被根除;3型病毒也接近被根除。在该地区,最后一例野生脊髓灰质炎病毒病例于1991年出现在秘鲁。目前仍有两个流行国家:阿富汗和巴基斯坦,但在野生脊髓灰质炎病毒未传播的国家也报告了输入性脊髓灰质炎病例。2012年5月,世界卫生大会宣布根除脊髓灰质炎是全球公共卫生的一项计划性紧急任务,并据此制定了《2013 - 2018年脊髓灰质炎根除及终结战略计划》。该计划有四个目标:1)检测并阻断所有脊髓灰质炎病毒传播,持续监测15岁以下儿童的急性弛缓性麻痹情况。2)加强免疫体系,在2016年第一季度前停用口服脊髓灰质炎疫苗。用含1型和3型血清型的二价口服疫苗替代三价口服脊髓灰质炎疫苗,并在所有免疫程序中引入灭活脊髓灰质炎疫苗,以维持对2型脊髓灰质炎病毒的免疫力。3)控制脊髓灰质炎病毒并认证传播阻断情况。4)规划利用抗击脊髓灰质炎行动及其对公共卫生的影响。该计划预计在2018年实现目标;此后将停止所有口服脊髓灰质炎疫苗的使用。免疫程序的改变将要求儿科医生根据日常实践中的不同情况为家庭提供建议和指导。