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夜间角膜塑形术引起的双眼功能变化。

Binocular function changes produced in response to overnight orthokeratology.

作者信息

Felipe-Marquez Gema, Nombela-Palomo María, Palomo-Álvarez Catalina, Cacho Isabel, Nieto-Bona Amelia

机构信息

Department of Optics II (Optometry & Vision) Faculty of Optics & Optometry, Complutense University of Madrid, Arcos de Jalon 118, 28037, Madrid, Spain.

Applied Vision Research Group, Department of Optics II (Optometry & Vision) Faculty of Optics & Optometry, Complutense University of Madrid, Madrid, Spain.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2017 Jan;255(1):179-188. doi: 10.1007/s00417-016-3554-0. Epub 2016 Nov 21.

Abstract

PURPOSE

To analyze the binocular function changes produced on subjects undergoing overnight orthokeratology (OK) treatment over short-term (3 months) and long-term (3 years) wear.

METHODS

A prospective, longitudinal study on young adult subjects with low to moderate myopia was carried out. Binocular function was assessed by the following sequence of tests: Distance and near horizontal phoria (Von Graefe technique), distance and near horizontal vergence ranges (Risley rotary prisms), accommodative convergence/accommodation (AC/A) ratio (gradient method) and the near point of convergence (standard push-up technique). The short-term sample consisted of: 21 subjects in the control group, 26 in a corneal refractive therapy (CRT) treatment lenses group and 25 in a Seefree treatment lenses group. Those subjects were evaluated at baseline and at a 3-month follow-up visit. Twenty one subjects were old CRT wearers that attended a 3-year follow-up visit (long-term group).

RESULTS

A statistically significant difference over the 3-month treatment was found for divergence at distance: the break point decreased 1.4 Δ (p = 0.0006) in the CRT group and the recovery point increased 1.2 Δ (p = 0.001) in the Seefree group. Also, the Seefree group had an exophoric trend of 2.3 Δ at near (p = 0.02) and a base-out break decrease of 2.3 Δ (p = 0.03). For the long-term group, only the base-out break point at distant vision showed a statistically significant difference of 4.9 Δ (p = 0.02).

CONCLUSIONS

OK induces minimal changes in the binocular function for either short-term or long-term periods, apart from a near exophoric trend over the short-term period.

摘要

目的

分析接受过夜角膜塑形术(OK)治疗的受试者在短期(3个月)和长期(3年)佩戴期间产生的双眼功能变化。

方法

对患有轻度至中度近视的年轻成年受试者进行了一项前瞻性纵向研究。通过以下测试序列评估双眼功能:远距离和近距离水平隐斜(von Graefe技术)、远距离和近距离水平聚散范围(Risley旋转棱镜)、调节性集合/调节(AC/A)比率(梯度法)以及集合近点(标准上推法)。短期样本包括:对照组21名受试者、角膜屈光治疗(CRT)治疗镜片组26名受试者和Seefree治疗镜片组25名受试者。这些受试者在基线和3个月随访时进行评估。21名受试者为长期佩戴CRT的使用者,参加了3年随访(长期组)。

结果

在3个月的治疗期间,远距离散开方面发现有统计学显著差异:CRT组的破裂点降低了1.4Δ(p = 0.0006),Seefree组的恢复点增加了1.2Δ(p = 0.001)。此外,Seefree组在近距离有2.3Δ的外隐斜趋势(p = 0.02),向外散开破裂减少了2.3Δ(p = 0.03)。对于长期组,仅远距离视力的向外散开破裂点显示出4.9Δ的统计学显著差异(p = 0.02)。

结论

除了短期内有近距离外隐斜趋势外,OK在短期或长期对双眼功能的影响极小。

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