Petruzzelli S, Palla A, Prediletto R, Mazzuca N, Pistolesi M, Giuntini C
J Nucl Med Allied Sci. 1989 Jan-Mar;33(1):45-8.
The use of 123I-N,N,N'trimethyl-N'-2-hydroxy-3-methyl-5-iodobenzyl-1,3-propanediami ne (123I-HIPDM) as a lung perfusion tracer in a patient with pulmonary embolism is shown. 123I-HIPDM is compared with 99mTc-labeled human albumin microspheres (HAM) using both planar and tomographic (SPECT) imaging. Pulmonary segmental defects are shown by 123I-HIPDM as well as by HAM, with a slightly better definition of perfused areas. Tomograms better show segmental shape of perfusion defects. 123I-HIPDM may be proposed as lung perfusion tracer for both clinical and experimental purposes.
展示了使用123I-N，N，N' -三甲基-N' -2-羟基-3-甲基-5-碘苄基-1,3-丙二胺（123I-HIPDM）作为肺灌注示踪剂在一名肺栓塞患者中的应用。使用平面和断层扫描（SPECT）成像将123I-HIPDM与99mTc标记的人白蛋白微球（HAM）进行比较。123I-HIPDM和HAM均显示出肺段缺损，灌注区域的清晰度略好。断层扫描能更好地显示灌注缺损的节段形状。123I-HIPDM可作为临床和实验用途的肺灌注示踪剂。
