School of Electronics Engineering, Kyungpook National University, Daegu, 702-701, South Korea.
School of Mechanical and Aerospace Engineering, Nanyang Technological University, 639798, Singapore.
Sci Rep. 2016 Nov 22;6:37524. doi: 10.1038/srep37524.
Continuous and non-invasive monitoring of hemodynamic parameters through unobtrusive wearable sensors can potentially aid in early detection of cardiac abnormalities, and provides a viable solution for long-term follow-up of patients with chronic cardiovascular diseases without disrupting the daily life activities. Electrocardiogram (ECG) and siesmocardiogram (SCG) signals can be readily acquired from light-weight electrodes and accelerometers respectively, which can be employed to derive systolic time intervals (STI). For this purpose, automated and accurate annotation of the relevant peaks in these signals is required, which is challenging due to the inter-subject morphological variability and noise prone nature of SCG signal. In this paper, an approach is proposed to automatically annotate the desired peaks in SCG signal that are related to STI by utilizing the information of peak detected in the sliding template to narrow-down the search for the desired peak in actual SCG signal. Experimental validation of this approach performed in conventional/controlled supine and realistic/challenging seated conditions, containing over 5600 heart beat cycles shows good performance and robustness of the proposed approach in noisy conditions. Automated measurement of STI in wearable configuration can provide a quantified cardiac health index for long-term monitoring of patients, elderly people at risk and health-enthusiasts.
通过非侵入式可穿戴传感器对血流动力学参数进行连续监测,有助于早期发现心脏异常,为慢性心血管疾病患者的长期随访提供了一种可行的解决方案,且不会干扰日常生活活动。心电图 (ECG) 和心冲击图 (SCG) 信号可以分别从重量轻的电极和加速度计中轻易获取,这些信号可用于推导收缩时间间隔 (STI)。为此,需要对这些信号中与 STI 相关的相关峰值进行自动且准确的注释,但由于 SCG 信号的个体间形态变异性和易受噪声影响的特点,这具有一定挑战性。本文提出了一种利用在滑动模板中检测到的峰值信息来缩小实际 SCG 信号中所需峰值搜索范围的方法,以自动注释 SCG 信号中与 STI 相关的期望峰值。在常规/受控仰卧位和现实/挑战性坐姿条件下进行的实验验证,包含超过 5600 个心跳周期,表明该方法在噪声条件下具有良好的性能和鲁棒性。在可穿戴配置中自动测量 STI 可以为患者、有风险的老年人和健康爱好者的长期监测提供量化的心脏健康指数。