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输卵管:在受精和早期胚胎发育中的作用

Oviduct: roles in fertilization and early embryo development.

作者信息

Li Shuai, Winuthayanon Wipawee

机构信息

School of Molecular BiosciencesCollege of Veterinary Medicine, Washington State University, Pullman, Washington, USA.

School of Molecular BiosciencesCollege of Veterinary Medicine, Washington State University, Pullman, Washington, USA

出版信息

J Endocrinol. 2017 Jan;232(1):R1-R26. doi: 10.1530/JOE-16-0302.

Abstract

Animal oviducts and human Fallopian tubes are a part of the female reproductive tract that hosts fertilization and pre-implantation development of the embryo. With an increasing understanding of roles of the oviduct at the cellular and molecular levels, current research signifies the importance of the oviduct on naturally conceived fertilization and pre-implantation embryo development. This review highlights the physiological conditions within the oviduct during fertilization, environmental regulation, oviductal fluid composition and its role in protecting embryos and supplying nutrients. Finally, the review compares different aspects of naturally occurring fertilization and assisted reproductive technology (ART)-achieved fertilization and embryo development, giving insight into potential areas for improvement in this technology.

摘要

动物的输卵管和人类的输卵管是女性生殖道的一部分,是胚胎受精和植入前发育的场所。随着对输卵管在细胞和分子水平上作用的认识不断加深,目前的研究表明输卵管对自然受孕的受精和植入前胚胎发育具有重要意义。本文综述着重介绍了受精过程中输卵管内的生理状况、环境调节、输卵管液成分及其在保护胚胎和提供营养方面的作用。最后,本文综述比较了自然受精与辅助生殖技术(ART)实现的受精和胚胎发育的不同方面,为该技术的潜在改进领域提供了见解。

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