School of Molecular Biosciences, Washington State University, Pullman, Washington, USA
Center for Reproductive Biology, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA
Reproduction. 2020 Mar 1;159(3):R125-R137. doi: 10.1530/REP-19-0189.
The oviduct (known as the fallopian tube in humans) is the site for fertilization and pre-implantation embryo development. Female steroid hormones, estrogen and progesterone, are known to modulate the morphology and function of cells in the oviduct. In this review, we focus on the actions of estrogen and progesterone on secretory, ciliated, and muscle cell functions and morphologies during fertilization, pre-implantation embryo development, and embryo transport in humans, laboratory rodents and farm animals. We review some aspects of oviductal anatomy and histology and discuss current assisted reproductive technologies (ARTs) that bypass the oviduct and their effects on embryo quality. Lastly, we review the causes of alterations in secretory, ciliated, and muscle cell functions that could result in embryo transport defects.
输卵管（在人类中称为输卵管）是受精和着床前胚胎发育的部位。女性甾体激素，雌激素和孕激素，已知可调节输卵管细胞的形态和功能。在这篇综述中，我们重点介绍了雌激素和孕激素在受精、着床前胚胎发育以及人类、实验啮齿动物和家畜胚胎运输过程中对分泌细胞、纤毛细胞和肌肉细胞功能和形态的作用。我们回顾了输卵管解剖和组织学的某些方面，并讨论了目前绕过输卵管的辅助生殖技术（ART）及其对胚胎质量的影响。最后，我们回顾了导致分泌细胞、纤毛细胞和肌肉细胞功能改变的原因，这些改变可能导致胚胎运输缺陷。
