Sisto T, Isola J
Department of Thoracic and Cardiovascular Surgery, Tampere University Central Hospital, Finland.
Ann Thorac Surg. 1989 Jun;47(6):884-6. doi: 10.1016/0003-4975(89)90027-1.
The long-term patency of the internal mammary artery (IMA) graft is better than that of the saphenous vein graft in coronary bypass procedures. The better patency is thought to be due in part to a relatively low incidence of atherosclerosis in the IMA. In the present study, the incidence of atherosclerosis in the IMA was evaluated in a consecutive Finnish autopsy series of 160 patients. Forty-five patients (28%) had marked occlusion in some coronary arteries as well as a history of angina pectoris. Only 5 (3.1%) of the 160 patients had notable stenosis in the IMA. Three of these 5 patients did not have coronary heart disease. Macroscopic or microscopic signs of atherosclerosis were found in 12.4% of 314 IMAs. We conclude that the low incidence of atherosclerosis in the IMAs in our study is due to their good resistance to the sclerotic process, although the incidence of ischemic heart diseases in Finland is among the highest in the world.
在冠状动脉搭桥手术中，乳内动脉（IMA）移植物的长期通畅性优于大隐静脉移植物。这种更好的通畅性被认为部分归因于IMA中动脉粥样硬化的发生率相对较低。在本研究中，在芬兰的一个连续尸检系列的160例患者中评估了IMA中动脉粥样硬化的发生率。45例患者（28%）在一些冠状动脉中存在明显闭塞以及有心绞痛病史。160例患者中只有5例（3.1%）在IMA中有明显狭窄。这5例患者中有3例没有冠心病。在314条IMA中，12.4%发现了动脉粥样硬化的宏观或微观迹象。我们得出结论，尽管芬兰缺血性心脏病的发生率在世界上处于最高水平之一，但我们研究中IMA中动脉粥样硬化的低发生率是由于它们对硬化过程具有良好的抵抗力。
