Kidwai Saera Suhail, Siddiqi Shaista Anwar, Nazir Lubna, Umer Tahira Parveen
Saera Suhail Kidwai, MCPS, FCPS Associate Professor, United Medical and Dental College, Karachi, Pakistan.
Shaista Anwar Siddiqi, FCPS (Neurology). Strokologist.
Pak J Med Sci. 2016 Sep-Oct;32(5):1077-1081. doi: 10.12669/pjms.325.10425.
To determine the frequency of knee osteoarthritis in adult patients with Diabetes mellitus and its association with body mass index (BMI) in kg/m and waist circumference (WC).
This is a cross-sectional comparative study at a tertiary hospital based in an industrial area of Karachi. Patient population comprised of all adult diabetic subjects. Clinical and demographic data was obtained with detailed musculoskeletal examination on all patients. BMI and WC were measured as kg/m and cm respectively. Data was analyzed on SPSS version 15.
A total of 413 subjects were recruited. Among them diabetic and non-diabetic subjects were 210 and 203 respectively. Mean age of diabetics was 50.7+-10.2 years as compared to non-diabetic subjects i.e. 49.5+-10.5 years. Proportion of male subjects was 72(34.3%) and 71(35.0) respectively in both groups. Mean duration of diabetes was 6.2 years. Frequency of knee osteoarthritis (OA) was found to be 52(24.8%) and 54(26.6%) in diabetic and non-diabetic respectively. Among the diabetic group 6 (18%) subjects with OA had normal BMI (18.5-22.9) whereas 4 (16%) were overweight (BMI 23-24.9) and 41(27.5%) were obese(BMI ≥25). Near 98% (n=51) of the diabetic patients with OA had high waist circumference. Females (n= 42, 31.1%) were more frequent than males (n=9, 16%) in the diabetic subjects with OA and a higher WC.
Both diabetic and non diabetic group did not show any difference in the frequency of knee OA. However, frequency of knee OA showed a significant difference between overweight and obese category of BMI.WC appears as a strong predictor of knee osteoarthritis.
确定成年糖尿病患者膝骨关节炎的发生率及其与体重指数（BMI，单位：kg/m²）和腰围（WC）的关系。
这是一项在卡拉奇工业区一家三级医院进行的横断面比较研究。研究对象为所有成年糖尿病患者。收集了所有患者的临床和人口统计学数据，并进行了详细的肌肉骨骼检查。分别以kg/m²和厘米为单位测量BMI和WC。数据采用SPSS 15版进行分析。
共招募了413名受试者。其中糖尿病患者和非糖尿病患者分别为210名和203名。糖尿病患者的平均年龄为50.7±10.2岁，非糖尿病患者为49.5±10.5岁。两组男性受试者比例分别为72名（34.3%）和71名（35.0%）。糖尿病平均病程为6.2年。发现糖尿病患者和非糖尿病患者膝骨关节炎（OA）的发生率分别为52名（24.8%）和54名（26.6%）。在糖尿病组中，6名（18%）患OA的受试者BMI正常（18.5 - 22.9），4名（16%）超重（BMI 23 - 24.9），41名（27.5%）肥胖（BMI≥25）。近98%（n = 51）患OA的糖尿病患者腰围较高。在患OA且腰围较高的糖尿病受试者中，女性（n = 42，31.1%）比男性（n = 9，16%）更常见。
糖尿病组和非糖尿病组在膝OA发生率上无差异。然而，膝OA发生率在超重和肥胖BMI类别之间存在显著差异。WC似乎是膝骨关节炎的一个强有力的预测指标。
