Iqbal Muhammad Navaid, Haidri Fakhir Raza, Motiani Balchand, Mannan Abdul
Liaquat National Hospital, Karachi.
J Pak Med Assoc. 2011 Aug;61(8):786-9.
To determine the frequency of factors associated with knee osteoarthritis.
A cross sectional study was conducted in the department of medicine at Liaquat National Hospital Karachi from September 2007 - March 2008 on patients diagnosed with osteoarthritis of knee. One hundred patients of age more than 18 years, and of either gender were consecutively included. Those patients with family history, occupations like farmers, mill workers and jack hammer operators, females with hormonal replacement therapy, patients with hyperparathyroidism, haemochromatosis and systemic lupus erythematosus were excluded. The patients were then graded on the basis of knee joint X-ray findings into four grades. The main outcome variables of the study were factors associated with osteoarthritis which included obesity, age, gender, smoking and anaemia.
The mean age was 56.28 +/- 8.786 years. The mean BMI was 29.434 +/- 7.849 years and mean Haemoglobin was 11.77 +/- 1.670 mg/dl. The frequency of factors associated with osteoarthritis was age 55 years in 60 (60%) patients. Gender included 74 (74%) females and 26 (26%) males. Smokers were 25 (25%), obesity was present in 33 (33%) and anaemia was present in 7 (50%) women and 16 (61.5%) males.
The study found that females of age greater than 55 years mostly noted to visit a tertiary care hospital due to knee osteoarthritis.
确定与膝关节骨关节炎相关因素的发生率。
2007年9月至2008年3月在卡拉奇利亚卡特国家医院内科对诊断为膝关节骨关节炎的患者进行了一项横断面研究。连续纳入100名年龄超过18岁、男女不限的患者。排除有家族病史的患者、从事农民、磨坊工人和手提钻操作员等职业的患者、接受激素替代疗法的女性患者、甲状旁腺功能亢进症患者、血色素沉着症患者和系统性红斑狼疮患者。然后根据膝关节X线检查结果将患者分为四个等级。该研究的主要结局变量是与骨关节炎相关的因素，包括肥胖、年龄、性别、吸烟和贫血。
平均年龄为56.28±8.786岁。平均体重指数为29.434±7.849，平均血红蛋白为11.77±1.670mg/dl。与骨关节炎相关因素的发生率为：60例（60%）患者年龄≥55岁；性别方面，女性74例（74%），男性26例（26%）；吸烟者25例（25%）；肥胖者33例（33%）；贫血者中，女性7例（50%），男性16例（61.5%）。
该研究发现，年龄大于55岁的女性大多因膝关节骨关节炎前往三级医疗机构就诊。
