Feng Xue-Min, Zhao Teng, Zhou Chun-Kui, Liu Jing-Yao
Department of Neurology, The First Hospital, Jilin University, Changchun, Jilin 130031, P.R. China.
Exp Ther Med. 2016 Nov;12(5):3485-3487. doi: 10.3892/etm.2016.3780. Epub 2016 Oct 4.
Central pontine myelinolysis (CPM), also known as osmotic demyelination syndrome, is a rare demyelinating disorder characterized by the loss of myelin in the center of the basis pontis. In this case report, an alcoholic patient with CPM and acquired demyelinating lesion of the basis pontis is described. The patient is a 70 year-old woman who presented with intermittent psychiatric symptoms and limb tremors following two months of alcohol abuse. During admission, magnetic resonance imaging (MRI) revealed hyperintensity on T2 weighted images and fluid-attenuated inversion-recovery imaging in the central pons without contrast enhancement. The patient's symptoms gradually improved following conservative treatment with vitamins B and B. The one month follow-up MRI showed a significant reduction of the pontine injury.
中央桥脑髓鞘溶解症（CPM），也称为渗透性脱髓鞘综合征，是一种罕见的脱髓鞘疾病，其特征是脑桥基底部中央的髓鞘丧失。在本病例报告中，描述了一名患有中央桥脑髓鞘溶解症和获得性脑桥基底部脱髓鞘病变的酒精性患者。该患者为一名70岁女性，在酗酒两个月后出现间歇性精神症状和肢体震颤。入院期间，磁共振成像（MRI）显示脑桥中央在T2加权像和液体衰减反转恢复成像上呈高信号，无强化。经维生素B和B保守治疗后，患者症状逐渐改善。1个月后的随访MRI显示脑桥损伤明显减轻。
