Yoon Bora, Shim Yong-Soo, Chung Sung-Woo
Department of Neurology, The Catholic University of Korea, Our Lady of Mercy Hospital 665, Bupyeong 6-dong, Bupyeong-gu, Incheon, Korea.
Alcohol Alcohol. 2008 Nov-Dec;43(6):647-9. doi: 10.1093/alcalc/agn050. Epub 2008 Aug 4.
Central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) are well-recognized syndromes that are related to various conditions such as rapid correction of hyponatremia and chronic alcoholism. We report a very case of a patient with dysarthria, dysphagia and psychiatric symptoms including abnormal behavior starting after alcohol withdrawal, with radiological evidence of CPM and EPM. There was little improvement in the dysarthria or psychiatric symptoms in the first month.
中央桥脑髓鞘溶解症(CPM)和脑桥外髓鞘溶解症(EPM)是公认的综合征,与多种情况相关,如低钠血症的快速纠正和慢性酒精中毒。我们报告了一例非常特殊的病例,患者在戒酒之后出现构音障碍、吞咽困难以及包括行为异常在内的精神症状,影像学检查显示存在中央桥脑髓鞘溶解症和脑桥外髓鞘溶解症。在第一个月,构音障碍和精神症状几乎没有改善。