Tran Dan N, Njuguna Benson, Mercer Timothy, Manji Imran, Fischer Lydia, Lieberman Marya, Pastakia Sonak D
Department of Pharmacy Practice, Purdue University College of Pharmacy, Indianapolis, IN 46202, USA.
Department of Pharmacy Practice, Purdue University College of Pharmacy, Indianapolis, IN 46202, USA; Department of Pharmacy, Moi Teaching and Referral Hospital, PO Box 3, Eldoret 30100, Kenya.
Cardiol Clin. 2017 Feb;35(1):125-134. doi: 10.1016/j.ccl.2016.08.008.
Cardiovascular disease (CVD) is the leading cause of global mortality and is expected to reach 23 million deaths by 2030. Eighty percent of CVD deaths occur in low-income and middle-income countries (LMICs). Although CVD prevention and treatment guidelines are available, translating these into practice is hampered in LMICs by inadequate health care systems that limit access to lifesaving medications. In this review article, we describe the deficiencies in the current LMIC supply chains that limit access to effective CVD medicines, and discuss existing solutions that are translatable to similar settings so as to address these deficiencies.
心血管疾病(CVD)是全球死亡的主要原因,预计到2030年将导致2300万人死亡。80%的心血管疾病死亡发生在低收入和中等收入国家(LMICs)。尽管有心血管疾病预防和治疗指南,但在低收入和中等收入国家,由于医疗保健系统不足,限制了获得救命药物的机会,这些指南难以转化为实际行动。在这篇综述文章中,我们描述了当前低收入和中等收入国家供应链中限制获得有效心血管疾病药物的缺陷,并讨论了可应用于类似情况以解决这些缺陷的现有解决方案。