Shakoori Pasha, Zhang Quanzhou, Le Anh D
Department of Oral and Maxillofacial Surgery/Pharmacology, University of Pennsylvania, School of Dental Medicine, 240 South 40th Street, Philadelphia, PA 19104-6030, USA.
Department of Oral and Maxillofacial Surgery/Pharmacology, University of Pennsylvania, School of Dental Medicine, 240 South 40th Street, Philadelphia, PA 19104-6030, USA.
Oral Maxillofac Surg Clin North Am. 2017 Feb;29(1):19-25. doi: 10.1016/j.coms.2016.08.009.
The field of tissue engineering and regenerative medicine has been rapidly expanded through multidisciplinary integration of research and clinical practice in response to unmet clinical needs for reconstruction of dental, oral, and craniofacial structures. The significance of the various types of stem cells, specifically mesenchymal stem cells derived from the orofacial tissues, ranging from dental pulp stem cells to periodontal ligament stem cells to mucosa/gingiva has been thoroughly investigated and their applications in tissue regeneration are outlined in this article.
为了满足牙、口腔和颅面结构重建方面未得到满足的临床需求,组织工程与再生医学领域通过研究与临床实践的多学科整合得到了迅速扩展。本文深入研究了各类干细胞的重要性,特别是源自口面部组织的间充质干细胞,从牙髓干细胞到牙周膜干细胞再到黏膜/牙龈干细胞,并概述了它们在组织再生中的应用。