Periodontol 2000. 2012 Jun;59(1):203-27. doi: 10.1111/j.1600-0757.2012.00443.x.
The aim of this review is to discuss the clinical utility of stem cells in periodontal regeneration by reviewing relevant literature that assesses the periodontal-regenerative potential of stem cells. We considered and described the main stem cell populations that have been utilized with regard to periodontal regeneration, including bone marrow-derived mesenchymal stem cells and the main dental-derived mesenchymal stem cell populations: periodontal ligament stem cells, dental pulp stem cells, stem cells from human exfoliated deciduous teeth, stem cells from apical papilla and dental follicle precursor cells. Research into the use of stem cells for tissue regeneration has the potential to significantly influence periodontal treatment strategies in the future.
本综述旨在通过回顾评估干细胞牙周再生潜能的相关文献,讨论干细胞在牙周再生中的临床应用。文中考虑并描述了已用于牙周再生的主要干细胞群体,包括骨髓间充质干细胞和主要的牙源性间充质干细胞群体:牙周膜干细胞、牙髓干细胞、人脱落乳牙干细胞、根尖乳头干细胞和牙周膜前体细胞。干细胞用于组织再生的研究有可能在未来对牙周治疗策略产生重大影响。