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小儿烧伤患者的疼痛管理:近期文献综述与未来方向

Pain Management in Pediatric Burn Patients: Review of Recent Literature and Future Directions.

作者信息

Pardesi Omar, Fuzaylov Gennadiy

机构信息

From the *Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston; and †Shriners Hospitals for Children - Boston.

出版信息

J Burn Care Res. 2017 Nov/Dec;38(6):335-347. doi: 10.1097/BCR.0000000000000470.

Abstract

Childhood burns are a profoundly traumatic and painful experience. Despite recognition of the prevalence of burn injuries in children and the severity of the associated pain, burn pain remains undertreated. At the same time, more evidence is emerging to suggest that undertreated pain has serious long-term medical and psychiatric consequences, many of which can be ameliorated with improved pain control. Pain in burn patients is, however, notoriously difficult to treat, perhaps because there is a chronic pain aspect underlying the acute pain that accompanies wound care and procedures. This difficulty is compounded by the fact that there are little data to guide decision making in these patients. This article aims to identify the best strategies to guide clinical practice through a review of the past 10 years' development in pediatric burn pain management. However, because clinical investigations remain limited in burned children, we also aim to draw attention to those areas where the data do not identify an optimal approach and further work is needed. Overall, in addition to just the traditional pharmacological approaches to pain, such as acetaminophen, benzodiazepines, and opioids, there is growing evidence to support more widespread use of regional anesthesia and novel technologies such as virtual reality. Starting with an improved understanding of the current state of the literature, we can identify areas of research and important questions whose answers will ultimately improve care and reduce suffering for this unfortunate population of children.

摘要

儿童烧伤是一种极具创伤性和痛苦的经历。尽管人们已经认识到儿童烧伤的普遍性以及相关疼痛的严重性,但烧伤疼痛仍未得到充分治疗。与此同时,越来越多的证据表明,未得到充分治疗的疼痛会产生严重的长期医学和精神后果,其中许多后果可以通过改善疼痛控制来缓解。然而,烧伤患者的疼痛 notoriously difficult to treat,这可能是因为在伤口护理和治疗过程中伴随的急性疼痛背后存在慢性疼痛因素。由于几乎没有数据可指导这些患者的决策,这一困难更加复杂。本文旨在通过回顾过去10年小儿烧伤疼痛管理的发展情况,确定指导临床实践的最佳策略。然而,由于对烧伤儿童的临床研究仍然有限,我们还旨在提请注意那些数据未能确定最佳方法且需要进一步研究的领域。总体而言,除了对乙酰氨基酚、苯二氮䓬类药物和阿片类药物等传统的疼痛药理学方法外,越来越多的证据支持更广泛地使用区域麻醉和虚拟现实等新技术。从更好地理解当前文献状况入手,我们可以确定研究领域和重要问题,其答案最终将改善护理并减轻这群不幸儿童的痛苦。

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