Cogen Jonathan D, Swanson Jonathan, Ong Thida
Division of Pulmonary Medicine, Department of Pediatrics, University of Washington, Seattle, WA, USA.
Division of Pediatric Radiology, Department of Radiology, University of Washington, Seattle, WA, USA.
Case Rep Pediatr. 2016;2016:2074970. doi: 10.1155/2016/2074970. Epub 2016 Nov 8.
Endobronchial carcinoid tumors are the most common intrabronchial tumors in children and adolescents. Common signs and symptoms include persistent cough and wheezing not responsive to bronchodilators, hemoptysis, and recurrent fever. Diagnosis is frequently made by imaging and direct visualization with flexible bronchoscopy; surgery remains the gold standard treatment, and lung-sparing resections should be performed whenever possible. Though carcinoid syndrome-characterized by flushing, palpitations, wheezing, shortness of breath, and diarrhea-has been found in association with adult bronchial carcinoid tumors, to our knowledge only one previous study has reported the presence of carcinoid syndrome in a pediatric patient with an endobronchial carcinoid. Here, we report a case of a 14-year-old girl with chronic cough found to have an endobronchial carcinoid tumor and signs and symptoms consistent with carcinoid syndrome.
支气管内类癌瘤是儿童和青少年中最常见的支气管内肿瘤。常见的体征和症状包括持续咳嗽、对支气管扩张剂无反应的喘息、咯血和反复发热。诊断通常通过影像学检查和柔性支气管镜直接观察来进行;手术仍然是金标准治疗方法,应尽可能进行肺保留切除术。虽然类癌综合征(以潮红、心悸、喘息、呼吸急促和腹泻为特征)已被发现与成人支气管类癌瘤有关,但据我们所知,此前仅有一项研究报告了一名患有支气管内类癌的儿科患者出现类癌综合征。在此,我们报告一例14岁慢性咳嗽女孩的病例,该女孩被发现患有支气管内类癌瘤,并伴有与类癌综合征一致的体征和症状。