Feder Idit, Wróbel Maciej, Duadi Hamootal, Jędrzejewska-Szczerska Małgorzata, Fixler Dror
Faculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Bar Ilan University, Israel.
Gdańsk University of Technology, Faculty of Electronics, Telecommunications and Informatics, Department of Metrology and Optoelectronics, Gabriela Narutowicza Str. 11/12, 80-233 Gdańsk, Poland.
Biomed Opt Express. 2016 Oct 21;7(11):4695-4701. doi: 10.1364/BOE.7.004695. eCollection 2016 Nov 1.
Human tissue is one of the most complex optical media since it is turbid and nonhomogeneous. We suggest a new optical method for sensing physiological tissue state, based on the collection of the ejected light at all exit angles, to receive the full scattering profile. We built a unique set-up for noninvasive encircled measurement. We use a laser, a photodetector and finger tissues-mimicking phantoms presenting different optical properties. Our method reveals an isobaric point, which is independent of the optical properties. We compared the new finger tissues-like phantoms to others samples and found the linear dependence between the isobaric point's angle and the exact tissue geometry. These findings can be useful for biomedical applications such as non-invasive and simple diagnostic of the fingertip joint, ear lobe and pinched tissues.
人体组织是最复杂的光学介质之一,因为它是浑浊且非均匀的。我们提出了一种新的光学方法来感知生理组织状态,该方法基于收集所有出射角度的出射光,以获取完整的散射分布。我们构建了一个用于非侵入性环绕测量的独特装置。我们使用激光、光电探测器和模拟具有不同光学特性的手指组织的体模。我们的方法揭示了一个与光学特性无关的等压点。我们将新型手指组织样体模与其他样本进行了比较,发现等压点角度与精确的组织几何形状之间存在线性关系。这些发现对于诸如指尖关节、耳垂和挤压组织的非侵入性和简单诊断等生物医学应用可能是有用的。