Hudgins Eric, Brown Mesha-Gay, Litt Brian, Davis Kathryn, Richardson Andrew G, Lucas Timothy
Department of Neurosurgery, The Hospital of the University of Pennsylvania.
Department of Neurology, University of Colorado Hospital.
Cureus. 2016 Oct 15;8(10):e831. doi: 10.7759/cureus.831.
Here we present a unique, but important seizure variant directly related to placement of subdural grids. Two distinct epileptogenic zones were identified, one which correlated with the patient's baseline seizures and a separate zone associated with atypical semiology and localization. Inspection of this zone at surgery revealed cortical deformation from the grid itself. The patient underwent successful surgical resection of the primary epileptogenic zone, but not that of the atypical zone. She remains seizure free at two years following surgery. Recognition of grid-induced seizures is important as they may confound the interpretation of intracranial electroencephalograms (iEEG) and mislead resective surgery.
在此,我们呈现一种独特但重要的癫痫发作变体,它与硬膜下电极片的放置直接相关。确定了两个不同的致痫区,一个与患者的基线癫痫发作相关,另一个与非典型症状学和定位相关。手术中检查该区域时发现,电极片本身导致了皮质变形。患者成功切除了主要致痫区,但未切除非典型区域。术后两年她一直无癫痫发作。认识到电极片诱发的癫痫发作很重要,因为它们可能会混淆颅内脑电图(iEEG)的解读,并误导切除性手术。