Voigt Robert G, Katusic Slavica K, Colligan Robert C, Killian Jill M, Weaver Amy L, Barbaresi William J
*Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX; Departments of †Health Sciences Research, and ‡Psychiatry and Psychology, Mayo Clinic, Rochester, MN; §Division of Developmental Medicine, Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA.
J Dev Behav Pediatr. 2017 Jan;38(1):1-11. doi: 10.1097/DBP.0000000000000358.
Previous research on the developmental course of attention-deficit/hyperactivity disorder (ADHD) is limited by biased clinic-referred samples and other methodological problems. Thus, questions about adult academic outcomes associated with childhood ADHD remain unanswered. Thus, the objective of this study was to describe academic outcomes in adulthood among incident cases of research-identified childhood ADHD versus non-ADHD referents from a population-based birth cohort.
Young adults with research-identified childhood ADHD (N = 232; mean age 27.0 yr; 72.0% men) and referents (N = 335; mean age 28.6 yr; 62.7% men) from a 1976 to 1982 birth cohort (N = 5699) were invited to participate in a followup study and were administered an academic achievement battery consisting of the basic reading component of the Woodcock-Johnson III Tests of Achievement (WJ-III) and the arithmetic subtest of the Wide Range Achievement Test-Third Edition (WRAT-3). Outcomes were compared between the 2 groups using linear regression models, adjusted for age, sex, and comorbid learning disability status.
Childhood ADHD cases scored from 3 to 5 grade equivalents lower on all academic tests compared with referents, with mean (SD) standard scores of 95.7 (8.4) versus 101.8 (8.1) in basic reading; 95.0 (9.3) versus 101.9 (8.5) in letterword identification; 98.2 (8.6) versus 103.2 (9.2) in passage comprehension; 95.7 (9.1) versus 100.9 (9.0) in word attack; and 87.8 (12.9) versus 98.0 (12.0) in arithmetic.
This is the first prospective, population-based study of adult academic outcomes of childhood ADHD. Our data provide evidence that childhood onset ADHD is associated with long-term underachievement in reading and math that may negatively impact ultimate educational attainment and occupational functioning in adulthood.
先前关于注意力缺陷多动障碍(ADHD)发展过程的研究受到临床转诊样本偏差及其他方法学问题的限制。因此,与儿童期ADHD相关的成人学业成果问题仍未得到解答。本研究的目的是描述基于人群的出生队列中,经研究确定的儿童期ADHD病例与非ADHD对照者在成年期的学业成果。
邀请1976年至1982年出生队列(共5699人)中经研究确定患有儿童期ADHD的年轻成年人(N = 232;平均年龄27.0岁;72.0%为男性)和对照者(N = 335;平均年龄28.6岁;62.7%为男性)参与一项随访研究,并对其进行一套学业成就测试,包括伍德科克-约翰逊III成就测验(WJ-III)的基本阅读部分和广泛成就测验第三版(WRAT-3)的算术子测验。使用线性回归模型比较两组的结果,并对年龄、性别和共病学习障碍状况进行了调整。
与对照者相比,儿童期ADHD病例在所有学业测试中的得分低3至5个年级当量,基本阅读的平均(标准差)标准分数分别为95.7(8.4)和101.8(8.1);字母-单词识别为95.0(9.3)和101.9(8.5);阅读理解为98.2(8.6)和103.2(9.2);单词攻击为95.7(9.1)和100.9(9.0);算术为87.8(12.9)和98.0(12.0)。
这是第一项关于儿童期ADHD成人学业成果的前瞻性、基于人群的研究。我们的数据提供了证据,表明儿童期起病的ADHD与阅读和数学方面的长期学业成绩不佳有关,这可能会对成年后的最终教育程度和职业功能产生负面影响。