Zhu Jianguo, Su Sheng, Li Haige
Department of Radiology, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Medicine (Baltimore). 2016 Nov;95(48):e5484. doi: 10.1097/MD.0000000000005484.
Angiomyofibroblastoma (AMFB) is an extremely rare disease. It commonly occurs in middle-aged females and mainly involves the vulvovaginal region. Pathological examination plays an important role in differentiating from other tumors. But far less published literature focus on the imaging characteristics of AMFB.
CLINICAL FINDINGS/DIAGNOSES: We reported a case of AMFB in a 73-year-old male, involving the mediastinum with computed tomography (CT) imaging and pathologic findings. Preoperative unenhanced CT scan of chest revealed a 6.9 × 7.4 × 9.3 cm mass with equal density, located in the posterior mediastinum. On contrast-enhanced CT images, the tumor presented moderate, heterogeneous enhancement. Due to the unclear interface between the tumor and adjacent tissues, this patient underwent operative partial resection of the tumor. The pathologic diagnosis was AMFB.
This tumor represents a further example of unusual location different from conventional AMFB. This case adds to the experience with AMFB by summarizing its characteristics, and also reviewing the literature.
血管肌纤维母细胞瘤（AMFB）是一种极为罕见的疾病。它常见于中年女性，主要累及外阴阴道区域。病理检查在与其他肿瘤的鉴别中起着重要作用。但关于AMFB影像学特征的文献报道却少得多。
临床发现/诊断：我们报告了一例73岁男性的AMFB病例，通过计算机断层扫描（CT）成像和病理检查发现肿瘤累及纵隔。术前胸部未增强CT扫描显示后纵隔有一个6.9×7.4×9.3 cm的等密度肿块。在增强CT图像上，肿瘤呈中度不均匀强化。由于肿瘤与相邻组织之间的界面不清，该患者接受了肿瘤部分切除术。病理诊断为AMFB。
该肿瘤是与传统AMFB不同的异常部位的又一实例。通过总结其特征并复习文献，此病例增加了对AMFB的认识。
