Jevsek Marko, Mounayer Charbel, Seruga Tomaz
Department of Radiology, University Clinical Center Maribor, Slovenia.
Department of Radiology, Dupuytren University Hospital, France.
Radiol Oncol. 2016 Nov 9;50(4):378-384. doi: 10.1515/raon-2016-0049. eCollection 2016 Dec 1.
Intra-arterial treatment of aneurysms by redirecting blood flow is a newer method. The redirection is based on a significantly more densely braided wire stent. The stent wall keeps the blood in the lumen of the stent and slows down the turbulent flow in the aneurysms. Stagnation of blood in the aneurysm sac leads to the formation of thrombus and subsequent exclusion of the aneurysm from the circulation. The aim of the study was to evaluate flow diverter device Pipeline for broad neck and giant aneurysm treatment.
Fifteen patients with discovered aneurysm of the internal carotid artery were treated between November 2010 and February 2014. The majority of aneurysms of the internal carotid artery were located intradural at the ophthalmic part of the artery. The patients were treated using a flow diverter device Pipeline, which was placed over the aneurysm neck. Treatment success was assessed clinically and angiographically using O'Kelly Marotta scale.
Control angiography immediately after the release of the stent showed stagnation of the blood flow in the aneurysm sac. In none of the patients procedural and periprocedural complications were observed. 6 months after the procedure, control CT or MR angiography showed in almost all cases exclusion of the aneurysm from the circulation and normal blood flow in the treated artery. Neurological status six months after the procedure was normal in all patients.
Treatment of aneurysms with flow diverter Pipeline device is a safe and significantly less time consuming method in comparison with standard techniques. This new method is a promising approach in treatment of broad neck aneurysms.
通过改变血流方向对动脉瘤进行动脉内治疗是一种较新的方法。这种血流方向的改变基于一种编织更为密集的金属丝支架。支架壁可使血液保持在支架管腔内,并减缓动脉瘤内的湍流。动脉瘤腔内血液停滞会导致血栓形成,随后使动脉瘤与循环系统隔绝。本研究的目的是评估用于治疗宽颈和巨大动脉瘤的血流导向装置Pipeline。
2010年11月至2014年2月期间,对15例已发现颈内动脉瘤的患者进行了治疗。大多数颈内动脉瘤位于动脉眼段的硬膜内。使用血流导向装置Pipeline对患者进行治疗,该装置放置在动脉瘤颈部上方。使用O'Kelly Marotta量表从临床和血管造影方面评估治疗效果。
支架释放后立即进行的对照血管造影显示动脉瘤腔内血流停滞。所有患者均未观察到手术中和围手术期并发症。术后6个月,对照CT或磁共振血管造影显示几乎所有病例中动脉瘤均与循环系统隔绝,且治疗动脉内血流正常。所有患者术后6个月的神经功能状态均正常。
与标准技术相比,使用血流导向装置Pipeline治疗动脉瘤是一种安全且耗时显著更少的方法。这种新方法在治疗宽颈动脉瘤方面是一种有前景的途径。