低强度激光疗法治疗灼口综合征的疗效:一项系统评价。

Efficacy of low level laser therapy in the treatment of burning mouth syndrome: A systematic review.

作者信息

Al-Maweri Sadeq Ali, Javed Fawad, Kalakonda Butchibabu, AlAizari Nader A, Al-Soneidar Walid, Al-Akwa Ameen

机构信息

Department of Oral Medicine and Diagnostic Sciences, AlFarabi Colleges, Riyadh, Saudi Arabia; Department of Oral Medicine, Faculty of Dentistry, Sanaa University, Yemen.

Department of General Dentistry, Eastman Institute for Oral Health, University of Rochester, 14620 Rochester, NY, USA.

出版信息

Photodiagnosis Photodyn Ther. 2017 Mar;17:188-193. doi: 10.1016/j.pdpdt.2016.11.017. Epub 2016 Dec 2.

Abstract

BACKGROUND

Burning mouth syndrome (BMS) is a chronic pain condition with indefinite cure, predominantly affecting post-menopausal women. The aim of this study was to systematically review the efficacy of low level laser therapy in the treatment of burning mouth syndrome (BMS).

METHODS

PubMed, Embase and Scopus were searched from date of inception till and including October 2016 using various combinations of the following keywords: burning mouth syndrome, BMS, stomatodynia, laser therapy, laser treatment and phototherapy. The inclusion criteria were: Prospective, retrospective and case series studies. Letter to editors, reviews, experimental studies, studies that were not published in English, theses, monographs, and abstracts presented in scientific events were excluded. Due to heterogeneity of data no statistical analyses were performed.

RESULTS

Ten clinical studies fulfilled the eligibility criteria, five of which were randomized clinical trials. In these studies, the laser wavelengths, power output and duration of irradiation ranged between 630-980nm, 20-300mW, 10s-15min, respectively. Most of studies reported laser to be an effective therapy strategy for management of BMS.

CONCLUSION

Majority of the studies showed that laser therapy seemed to be effective in reducing pain in BMS patients. However, due to the varied methodologies and substantial variations in laser parameters among these studies, more clinical trials are required to ascertain the efficacy of laser for treating BMS.

摘要

背景

灼口综合征(BMS)是一种难以治愈的慢性疼痛疾病,主要影响绝经后女性。本研究的目的是系统评价低强度激光疗法治疗灼口综合征(BMS)的疗效。

方法

从数据库建库至2016年10月(含10月),使用以下关键词的不同组合在PubMed、Embase和Scopus数据库中进行检索:灼口综合征、BMS、口腔疼痛、激光疗法、激光治疗和光疗。纳入标准为:前瞻性、回顾性和病例系列研究。排除给编辑的信、综述、实验研究、非英文发表的研究、论文、专著以及在科学会议上发表的摘要。由于数据的异质性,未进行统计分析。

结果

10项临床研究符合纳入标准,其中5项为随机临床试验。在这些研究中,激光波长、输出功率和照射时间分别在630 - 980nm、20 - 300mW、10秒 - 15分钟之间。大多数研究报告激光是治疗BMS的有效治疗策略。

结论

大多数研究表明激光疗法似乎能有效减轻BMS患者的疼痛。然而,由于这些研究中的方法多样且激光参数存在很大差异,则需要更多的临床试验来确定激光治疗BMS的疗效。

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