Baauw Marieke, van Hooff Miranda L, Spruit Maarten
Department of Orthopaedic Surgery, Sint Maartenskliniek, Nijmegen, the Netherlands.
JBJS Rev. 2016 Nov 8;4(11). doi: 10.2106/JBJS.RVW.15.00119.
Many treatment options are available for the revision of large acetabular defects. Debate continues as to which technique is most effective.
A systematic review was performed according to the Meta-analysis of Observational Studies in Epidemiology (MOOSE) guidelines to evaluate the effectiveness of interventions for large acetabular defects. Quality assessment was performed next with use of 8 items of the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist for reports of observational studies. Large acetabular defects were defined as American Academy of Orthopaedic Surgeons (AAOS) type III or IV or Paprosky type 3A or 3B. Outcomes included re-revision, radiographic loosening, complications, and clinical outcomes.
We found 7 different treatment options for large acetabular defects in 20 included studies: antiprotrusio cage (8 studies), Trabecular Metal (Zimmer) augment and shell (4 studies), bone impaction grafting with a metal mesh (2 studies), hemispherical implant with hook and flanges (2 studies), Trabecular Metal augment or structural allograft with cup (2 studies), cup-cage reconstruction (1 study), and custom-made triflange component (1 study).
Trabecular Metal augments and shells gave the most promising results in terms of the re-revision rate and radiographic loosening. Reconstruction with an antiprotrusio cage was the most frequently reported technique, with good results in a physically low-demand elderly population. Bone impaction grafting seems not appropriate for pelvic discontinuity and prone to failure in patients with Paprosky type-3B defects. In those cases, a custom-made triflange implant or a cup-cage reconstruction might be the best alternative, but few reports of sufficient quality are available yet.
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
对于大型髋臼缺损的翻修,有多种治疗选择。关于哪种技术最有效,争论仍在继续。
根据流行病学观察性研究的Meta分析(MOOSE)指南进行系统评价,以评估大型髋臼缺损干预措施的有效性。接下来,使用流行病学观察性研究报告强化(STROBE)清单的8项内容对观察性研究报告进行质量评估。大型髋臼缺损定义为美国矫形外科医师学会(AAOS)III型或IV型或Paprosky 3A型或3B型。结果包括再次翻修、影像学松动、并发症和临床结果。
在纳入的20项研究中,我们发现了7种针对大型髋臼缺损的不同治疗选择:防髋臼前突笼(8项研究)、小梁金属(捷迈)增强物和髋臼杯(4项研究)、金属网骨打压植骨(2项研究)、带钩和翼缘的半球形植入物(2项研究)、小梁金属增强物或结构性同种异体骨与髋臼杯(2项研究)、髋臼杯-笼重建(1项研究)以及定制三翼组件(1项研究)。
就再次翻修率和影像学松动而言,小梁金属增强物和髋臼杯取得了最有前景的结果。防髋臼前突笼重建是报告最频繁的技术,在身体需求较低的老年人群中效果良好。骨打压植骨似乎不适用于骨盆连续性中断,且在Paprosky 3B型缺损患者中容易失败。在这些情况下,定制三翼植入物或髋臼杯-笼重建可能是最佳选择,但目前高质量的报告较少。
治疗性IV级。有关证据水平的完整描述,请参阅作者指南。