Fredj G, Dietlin F, Fredj D, Schwarzenberg L, Jasmin C, Meyer P, Misset J L
Hôpital Paul Brousse, Villejuif, France.
Int J Clin Pharmacol Ther Toxicol. 1989 Aug;27(8):408-10.
On the basis of a similarity between certain neurological symptoms of AIDS and Alzheimer's disease, the authors studied the effects of tetrahydroaminoacridine (THA) in 9 patients with HIV infection. After 2 months of treatment, the preliminary results showed a significant increase in CD4 lymphocyte count as well as a decrease in p24 antigen level in 8 patients, of whom 4 became negative for the p24 antigen.
基于艾滋病的某些神经症状与阿尔茨海默病之间的相似性,作者研究了四氢氨基吖啶(THA)对9例HIV感染患者的影响。治疗2个月后,初步结果显示8例患者的CD4淋巴细胞计数显著增加,p24抗原水平降低,其中4例p24抗原呈阴性。