Kerr William C, Ye Yu, Greenfield Thomas K, Williams Edwina, Lui Camillia K, Li Libo, Lown E Anne
Alcohol Research Group, Public Health Institute, 6001 Shellmound St., Suite 450, Emeryville, CA 94608, USA.
Alcohol Research Group, Public Health Institute, 6001 Shellmound St., Suite 450, Emeryville, CA 94608, USA.
Prev Med. 2017 Feb;95:47-51. doi: 10.1016/j.ypmed.2016.12.006. Epub 2016 Dec 6.
Heavy episodic drinking is a well-established risk factor for heart disease, diabetes, certain cancers, stroke, hypertension and injuries, however, little is known about whether health problems precipitate changes in subsequent drinking patterns. Retrospective cohort analyses of heavy drinking by decade were conducted using data from the 2010 U.S. National Alcohol Survey (n=5240). Generalized estimating equations models were used to predict any, monthly, and weekly heavy (5+) drinking occasions across decades of life following a diagnosis of hypertension, heart problems, diabetes, stroke, cancer, or serious injury. Experiencing heart problems was associated with higher odds of reduced weekly heavy drinking (adjusted odds ratio (OR)=3.5; 95% confidence interval (CI); 1.7-7.4). The onset of diabetes was also associated with higher odds of reducing any heavy drinking over the decade (OR=1.7; 95% CI; 1.1-2.6). Cancer survivors were less likely to report no heavy drinking (OR=0.5; 95% CI; 0.3-0.8) or no weekly heavy drinking (OR=0.3; 95% CI; 0.2-0.7). Hypertension, stroke and injury were not found to have any significant associations. Reduced heavy drinking was more likely to be reported by Black drinkers following heart problems and Whites following a diabetes diagnosis. Increased heavy drinking following a cancer diagnosis was significant among women and Whites. Future studies on alcohol's heath and mortality risks should take into consideration effects of health problems on drinking patterns. Additionally, study results support increased prevention efforts targeting heavy drinking among cancer survivors, especially White women, and individuals with or being treated for hypertension.
大量饮酒是心脏病、糖尿病、某些癌症、中风、高血压和受伤的既定风险因素,然而,对于健康问题是否会促使后续饮酒模式发生变化,人们却知之甚少。利用2010年美国国家酒精调查(n=5240)的数据,对按十年划分的大量饮酒情况进行了回顾性队列分析。使用广义估计方程模型来预测在被诊断患有高血压、心脏病、糖尿病、中风、癌症或严重受伤后的数十年中,出现任何、每月和每周大量(5次及以上)饮酒情况的概率。经历心脏病与每周大量饮酒减少的较高概率相关(调整后的优势比(OR)=3.5;95%置信区间(CI);1.7 - 7.4)。糖尿病的发病也与在这十年中减少任何大量饮酒的较高概率相关(OR=1.7;95% CI;1.1 - 2.6)。癌症幸存者不太可能报告没有大量饮酒(OR=0.5;95% CI;0.3 - 0.8)或没有每周大量饮酒(OR=0.3;95% CI;0.2 - 0.7)。未发现高血压、中风和受伤有任何显著关联。黑人饮酒者在患心脏病后以及白人在被诊断患有糖尿病后更有可能报告减少大量饮酒。癌症诊断后大量饮酒增加在女性和白人中较为显著。未来关于酒精对健康和死亡风险的研究应考虑健康问题对饮酒模式的影响。此外,研究结果支持加大针对癌症幸存者,尤其是白人女性以及患有高血压或正在接受高血压治疗的个体的大量饮酒预防力度。