Kerr William C, Ye Yu, Cherpitel Cheryl J
Alcohol Research Group, Public Health Institute, Emeryville, CA, USA
Alcohol Research Group, Public Health Institute, Emeryville, CA, USA.
Alcohol Alcohol. 2015 Sep;50(5):573-8. doi: 10.1093/alcalc/agv044. Epub 2015 May 12.
To estimate the risk of injury associated with the frequency of heavy drinking days overall and for black, white and Hispanic drinkers in a US sample.
Data are from the 2010 National Alcohol Survey and included 6506 respondents comprising the landline sample. Analyses utilize Cox proportional hazards models with age as the timescale in a retrospective cohort design. Life-course drinking is determined by age of onset and questions on heavy drinking by decade of life. The outcome measure is having had a serious injury at a certain age. Models estimate the risk of injury in relation to heavy drinking in each year controlling for demographics, risk taking and time varying measures of smoking and chronic disease.
Results indicate that the risk of injury increases with the frequency of heavy drinking days to a hazard ratio of 2.14 (1.45-3.14) for daily heavy drinkers. Risks for white respondents were similar to the overall results but different risk relationships were found for black respondents among whom only daily heavy drinkers had increased risk of 4.09 (2.11-7.93), and for Hispanic respondents where elevated risk was seen among yearly heavy drinkers 2.71 (1.29-5.68), with a similar risk estimate for monthly heavy drinkers but lower and non-significant risks found for more frequent heavy drinking categories.
Different risk relationships were found across race/ethnicity groups suggesting elevated risk with less frequent heavy drinking among Hispanic respondents and very high risk from daily heavy drinking among black respondents.
在美国一个样本中,估计总体以及黑人、白人、西班牙裔饮酒者中与重度饮酒日频率相关的受伤风险。
数据来自2010年全国酒精调查,包括6506名通过固定电话样本选取的受访者。分析采用Cox比例风险模型,以年龄作为回顾性队列设计中的时间尺度。终生饮酒情况由开始饮酒年龄和按生命十年划分的重度饮酒问题确定。结局指标是在特定年龄遭受严重伤害。模型在控制人口统计学、冒险行为以及吸烟和慢性病随时间变化的测量指标的情况下,估计每年与重度饮酒相关的受伤风险。
结果表明,受伤风险随着重度饮酒日频率的增加而升高,每日重度饮酒者的风险比为2.14(1.45 - 3.14)。白人受访者的风险与总体结果相似,但黑人受访者的风险关系有所不同,其中只有每日重度饮酒者的风险增加,为4.09(2.11 - 7.93);西班牙裔受访者中,每年重度饮酒者的风险升高,为2.71(1.29 - 5.68),每月重度饮酒者的风险估计相似,但更频繁重度饮酒类别中的风险较低且无统计学意义。
不同种族/族裔群体之间存在不同的风险关系,表明西班牙裔受访者中重度饮酒频率较低时风险升高,而黑人受访者中每日重度饮酒风险极高。