威尔士东南部多发性硬化症的发病率和死亡率。
The incidence and mortality of multiple sclerosis in south east Wales.
作者信息
Hennessy A, Swingler R J, Compston D A
机构信息
Department of Medicine, University of Wales College of Medicine, Cardiff, UK.
出版信息
J Neurol Neurosurg Psychiatry. 1989 Sep;52(9):1085-9. doi: 10.1136/jnnp.52.9.1085.
Abstract
The incidence of multiple sclerosis was shown to be 8.2/10(5)/year (definite or probable 5.4 and suspected 2.8/10(5)/year) during a 3 year prospective study carried out in an area of south east Wales which has a high prevalence of the disease (120/10(5). Mortality in affected individuals who were prevalent at the start of the survey was 3.1/10(5)/year; many deaths resulted from direct complications of multiple sclerosis but 38% were due to unrelated causes. The rate at which new cases were identified approximately matched deletions from the register arising from death, outward migration and other causes so that prevalence did not change significantly during the survey (1985-1988).
摘要
在威尔士东南部一个该疾病高发地区（患病率为120/10⁵）进行的为期3年的前瞻性研究显示，多发性硬化症的发病率为8.2/10⁵/年（确诊或疑似病例为5.4/10⁵/年，疑似病例为2.8/10⁵/年）。在调查开始时已患该病的个体死亡率为3.1/10⁵/年；许多死亡是由多发性硬化症的直接并发症导致的，但38%是由无关原因引起的。新病例的发现率与因死亡、外迁及其他原因从登记册中删除的病例数大致相当，因此在调查期间（1985 - 1988年）患病率没有显著变化。
相似文献
1
The incidence and mortality of multiple sclerosis in south east Wales.威尔士东南部多发性硬化症的发病率和死亡率。
J Neurol Neurosurg Psychiatry. 1989 Sep;52(9):1085-9. doi: 10.1136/jnnp.52.9.1085.
2
The prevalence of multiple sclerosis in south east Wales.威尔士东南部多发性硬化症的患病率。
J Neurol Neurosurg Psychiatry. 1988 Dec;51(12):1520-4. doi: 10.1136/jnnp.51.12.1520.
3
Multiple sclerosis in south Cambridgeshire: incidence and prevalence based on a district register.剑桥郡南部的多发性硬化症：基于地区登记册的发病率和患病率
J Epidemiol Community Health. 1996 Jun;50(3):274-9. doi: 10.1136/jech.50.3.274.
4
A prospective study of the incidence, prevalence and mortality of multiple sclerosis in Leeds.利兹市多发性硬化症发病率、患病率及死亡率的前瞻性研究。
J Neurol. 2002 Mar;249(3):260-5. doi: 10.1007/s004150200002.
5
Survival and cause of death in multiple sclerosis: a prospective population-based study.多发性硬化症的生存率及死因：一项基于人群的前瞻性研究。
J Neurol Neurosurg Psychiatry. 2008 Sep;79(9):1016-21. doi: 10.1136/jnnp.2007.127332. Epub 2008 Feb 26.
6
The prevalence of multiple sclerosis in south east Wales.威尔士东南部多发性硬化症的患病率。
J Neurol Neurosurg Psychiatry. 1989 Aug;52(8):1017. doi: 10.1136/jnnp.52.8.1017.
7
High incidence and prevalence of multiple sclerosis in south east Scotland: evidence of a genetic predisposition.苏格兰东南部多发性硬化症的高发病率和患病率：遗传易感性证据。
J Neurol Neurosurg Psychiatry. 1998 Jun;64(6):730-5. doi: 10.1136/jnnp.64.6.730.
8
Increasing prevalence and incidence of multiple sclerosis in South East Wales.威尔士东南部多发性硬化症的患病率和发病率不断上升。
J Neurol Neurosurg Psychiatry. 2009 Apr;80(4):386-91. doi: 10.1136/jnnp.2008.144667. Epub 2008 Oct 17.
9
Multiple sclerosis in the north Cambridgeshire districts of East Anglia.东盎格利亚剑桥郡北部地区的多发性硬化症
J Neurol Neurosurg Psychiatry. 1995 Jul;59(1):71-6. doi: 10.1136/jnnp.59.1.71.
10
Demographic characteristics of multiple sclerosis in south east Wales.威尔士东南部多发性硬化症的人口统计学特征。
Neuroepidemiology. 1990;9(2):68-77. doi: 10.1159/000110753.
引用本文的文献
1
Multiple sclerosis and COVID-19: Assessing risk perception, patient behaviors and access to disease-modifying therapies.多发性硬化症和 COVID-19：评估风险认知、患者行为和获得疾病修正治疗的机会。
Mult Scler Relat Disord. 2022 Dec;68:104121. doi: 10.1016/j.msard.2022.104121. Epub 2022 Aug 17.
2
Clinical Outcomes of Escalation vs Early Intensive Disease-Modifying Therapy in Patients With Multiple Sclerosis.多发性硬化症患者强化治疗与早期强化疾病修正治疗的临床结局。
JAMA Neurol. 2019 May 1;76(5):536-541. doi: 10.1001/jamaneurol.2018.4905.
3
Seasonal variation in multiple sclerosis relapse.多发性硬化症复发的季节性变化。
J Neurol. 2017 Jun;264(6):1059-1067. doi: 10.1007/s00415-017-8485-0. Epub 2017 Apr 19.
4
A longitudinal model for disease progression was developed and applied to multiple sclerosis.开发了一种疾病进展的纵向模型并将其应用于多发性硬化症。
J Clin Epidemiol. 2015 Nov;68(11):1355-65. doi: 10.1016/j.jclinepi.2015.05.003. Epub 2015 May 14.
5
Incidence and prevalence of multiple sclerosis in Europe: a systematic review.欧洲多发性硬化症的发病率和患病率：系统评价。
BMC Neurol. 2013 Sep 26;13:128. doi: 10.1186/1471-2377-13-128.
6
Incidence of multiple sclerosis in the United Kingdom : findings from a population-based cohort.英国多发性硬化症的发病率：基于人群队列的研究结果
J Neurol. 2007 Dec;254(12):1736-41. doi: 10.1007/s00415-007-0602-z. Epub 2007 Oct 1.
7
Latitudinal variation in the prevalence of multiple sclerosis in Ireland, an effect of genetic diversity.爱尔兰多发性硬化症患病率的纬度变化：遗传多样性的影响
J Neurol Neurosurg Psychiatry. 2004 Apr;75(4):572-6. doi: 10.1136/jnnp.2003.012666.
8
Multiple sclerosis in Northern Ireland: a historical and global perspective.北爱尔兰的多发性硬化症：历史与全球视角
Ulster Med J. 2000 Nov;69(2):97-105.
9
Multiple sclerosis in south Cambridgeshire: incidence and prevalence based on a district register.剑桥郡南部的多发性硬化症：基于地区登记册的发病率和患病率
J Epidemiol Community Health. 1996 Jun;50(3):274-9. doi: 10.1136/jech.50.3.274.
10
Prevalence of multiple sclerosis in Rochdale.罗奇代尔多发性硬化症的患病率。
J Neurol Neurosurg Psychiatry. 1996 Oct;61(4):415-7. doi: 10.1136/jnnp.61.4.415.
本文引用的文献
1
Observations on the prevalence of multiple sclerosis in Northern Scotland.苏格兰北部多发性硬化症患病率观察
Brain. 1956 Dec;79(4):635-54. doi: 10.1093/brain/79.4.635.
2
Multiple sclerosis in the Orkney and Shetland Islands. I: Epidemiology, clinical factors, and methodology.奥克尼群岛和设得兰群岛的多发性硬化症。I：流行病学、临床因素及方法学
J Epidemiol Community Health. 1980 Dec;34(4):229-39. doi: 10.1136/jech.34.4.229.
3
New diagnostic criteria for multiple sclerosis: guidelines for research protocols.多发性硬化症的新诊断标准：研究方案指南。
Ann Neurol. 1983 Mar;13(3):227-31. doi: 10.1002/ana.410130302.
4
The chief scientist reports ... multiple sclerosis in North East Scotland.
Health Bull (Edinb). 1984 May;42(3):151-6.
5
Declining incidence of multiple sclerosis in the Orkney Islands.
Neurology. 1985 Apr;35(4):545-51. doi: 10.1212/wnl.35.4.545.
6
The distribution of multiple sclerosis in the United Kingdom.英国多发性硬化症的分布情况。
J Neurol Neurosurg Psychiatry. 1986 Oct;49(10):1115-24. doi: 10.1136/jnnp.49.10.1115.
7
The epidemiology of multiple sclerosis in three Australian cities: Perth, Newcastle and Hobart.澳大利亚三个城市（珀斯、纽卡斯尔和霍巴特）的多发性硬化症流行病学。
Brain. 1988 Feb;111 ( Pt 1):1-25. doi: 10.1093/brain/111.1.1.
8
The prevalence of multiple sclerosis in south east Wales.威尔士东南部多发性硬化症的患病率。
J Neurol Neurosurg Psychiatry. 1988 Dec;51(12):1520-4. doi: 10.1136/jnnp.51.12.1520.
9
The contribution of mortality statistics to the study of multiple sclerosis in Australia.死亡率统计数据对澳大利亚多发性硬化症研究的贡献。
J Neurol Neurosurg Psychiatry. 1989 Jan;52(1):1-7. doi: 10.1136/jnnp.52.1.1.
10
Prevalence of multiple sclerosis in north-east Scotland.苏格兰东北部多发性硬化症的患病率。
Br Med J. 1978 Jul 29;2(6133):314-6. doi: 10.1136/bmj.2.6133.314.
Zotero 插件