Shepherd D I, Summers A
Department of Neurology, North Manchester General Hospital, UK.
J Neurol Neurosurg Psychiatry. 1996 Oct;61(4):415-7. doi: 10.1136/jnnp.61.4.415.
The prevalence of multiple sclerosis in the Rochdale Metropolitan Borough in the north east of Greater Manchester has been established. Case ascertainment was partly prospective via a neurological register from 1979 and by contact with general practitioners, therapists, and social services. On prevalence day, 1 January 1989, 254 patients with multiple sclerosis were living in Rochdale. The overall prevalence was 122/100,000 population and 96/100,000 population for probable cases only. The peak rate for women aged 35 to 44 years was 437/100,000 population and for men aged 45 to 54 years 221/100,000. Familial multiple sclerosis was present in 10.8% of families. In this, the first study in north west England, the prevalence of multiple sclerosis in Rochdale is similar to that in southern England and Wales but lower than that in Scotland.
大曼彻斯特东北部罗奇代尔都会区多发性硬化症的患病率已确定。病例确诊部分通过1979年起的神经科登记册，并与全科医生、治疗师和社会服务部门联系进行。在患病率统计日，即1989年1月1日，有254名多发性硬化症患者居住在罗奇代尔。总体患病率为每10万人口122例，仅可能病例的患病率为每10万人口96例。35至44岁女性的患病率峰值为每10万人口437例，45至54岁男性为每10万人口221例。10.8%的家庭存在家族性多发性硬化症。在这项英格兰西北部的首次研究中，罗奇代尔多发性硬化症的患病率与英格兰南部和威尔士相似，但低于苏格兰。
