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美国年轻男性和女性肺癌发病率下降:一项队列分析。

Declining lung cancer rates among young men and women in the United States: a cohort analysis.

作者信息

Devesa S S, Blot W J, Fraumeni J F

机构信息

Division of Cancer Etiology, National Cancer Institute, Bethesda, MD 20892.

出版信息

J Natl Cancer Inst. 1989 Oct 18;81(20):1568-71. doi: 10.1093/jnci/81.20.1568.

Abstract

Although overall age-adjusted rates of mortality from lung cancer in the United States continue to rise, rates at ages below 45 years have begun to decline. In this report we show that the decrease is greatest among white men, with a 29% drop between the mid-1970s and mid-1980s, but a decrease also occurred among black men and white and black women. Cohort analyses revealed that the rates of lung cancer peaked among men born around 1925-1930 and among women born around 1935-1940, and have declined thereafter. If these trends continue, overall lung cancer mortality rates will start to decline in the 1990s among men and after the year 2000 among women.

摘要

尽管美国肺癌的总体年龄调整死亡率持续上升,但45岁以下人群的死亡率已开始下降。在本报告中,我们表明,白人男性的下降幅度最大,在20世纪70年代中期至80年代中期下降了29%,不过黑人男性以及白人女性和黑人女性的死亡率也出现了下降。队列分析显示,肺癌发病率在出生于1925年至1930年左右的男性以及出生于1935年至1940年左右的女性中达到峰值,此后便开始下降。如果这些趋势持续下去,肺癌总体死亡率将在20世纪90年代在男性中开始下降,在2000年之后在女性中开始下降。

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